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Complementary and Integrative Therapies for Childhood Atopic Dermatitis
Open AccessArticle

Topical and Oral Therapies for Childhood Atopic Dermatitis and Plaque Psoriasis

1
Center for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA
2
Department of Pathology, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA
3
Department of Social Sciences & Health Policy, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA
4
Department of Dermatology, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark
*
Author to whom correspondence should be addressed.
Children 2019, 6(11), 125; https://doi.org/10.3390/children6110125
Received: 19 August 2019 / Revised: 24 October 2019 / Accepted: 1 November 2019 / Published: 5 November 2019
(This article belongs to the Special Issue Atopic Dermatitis and Psoriasis in Children)
Background: Treatment of atopic dermatitis and psoriasis in children is difficult due to lack of standardized treatment guidelines and few FDA-approved treatment options. Treatments approved for adults may be used off-label in pediatric patients. Objective: This review evaluates the topical and oral treatment options available, including off-label uses, and provides a basic therapeutic guideline for pediatric atopic dermatitis and psoriasis. Methods: A PubMed review of topical and systemic treatments for pediatric psoriasis and atopic dermatitis with information regarding age, efficacy, dosing, contra-indications, adverse events, and off-label treatments. Results: The search identified seven topical and five systemic treatments that are routinely employed to treat pediatric atopic dermatitis and psoriasis. Limitations: Standardized guidelines regarding treatment choice, dosing, and long-term safety are scarce. Reviews may be subject to ascertainment bias. Conclusions: Current treatment guidelines are based on clinical experience and expert advice with few treatments officially approved for atopic dermatitis and psoriasis in children. View Full-Text
Keywords: children; pediatrics; psoriasis; atopic dermatitis; treatment children; pediatrics; psoriasis; atopic dermatitis; treatment
MDPI and ACS Style

Frantz, T.; Wright, E.G.; Balogh, E.A.; Cline, A.; Adler-Neal, A.L.; Feldman, S.R. Topical and Oral Therapies for Childhood Atopic Dermatitis and Plaque Psoriasis. Children 2019, 6, 125.

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