Next Article in Journal
Identification of Heavy Tobacco Smoking Predictors-Influence of Marijuana Consuming Peers and Truancy among College Students
Next Article in Special Issue
Endoscopic Diagnosis of Biliary Stricture Combined with Digital Cholangioscope: A Case Series
Previous Article in Journal
Psychological Effects of Motivational Aquatic Resistance Interval Training and Nutritional Education in Older Women
Previous Article in Special Issue
Analysis of Endoscopic Evaluation Reliability for Ulcerative Colitis in Histological Remission
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Healthcare
Volume 9
Issue 12
10.3390/healthcare9121668
healthcare-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Efficacy and Safety of Peroral Endoscopic Myotomy for Esophageal Achalasia and Achalasia-Related Diseases in Patients Aged 75 Years and Over

by
Jun Nakamura
1,2,
Takuto Hikichi
1,*,
Minami Hashimoto
1,2,
Mika Takasumi
2,
Tsunetaka Kato
1,2,
Ryoichiro Kobashi
1,2,
Takumi Yanagita
2,
Rei Suzuki
2,
Mitsuru Sugimoto
2,
Yuki Sato
2,
Hiroki Irie
2,
Tadayuki Takagi
2,
Masao Kobayakawa
1,3 and
Hiromasa Ohira
2
1
Department of Endoscopy, Fukushima Medical University Hospital, Fukushima 960-1295, Japan
2
Department of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima 960-1295, Japan
3
Medical Research Center, Fukushima Medical University, Fukushima 960-1295, Japan
*
Author to whom correspondence should be addressed.
Healthcare 2021, 9(12), 1668; https://doi.org/10.3390/healthcare9121668
Submission received: 3 October 2021 / Revised: 21 November 2021 / Accepted: 27 November 2021 / Published: 1 December 2021
(This article belongs to the Special Issue The Advanced Role of Gastrointestinal Endoscopy for Inflammatory Disease)
Browse Figures
Versions Notes

Abstract

Peroral endoscopic myotomy (POEM) has become a popular treatment for esophageal achalasia and other esophageal motility disorders. However, its efficacy and safety in elderly patients are unclear. To clarify that, we reviewed the medical records of patients who underwent POEM in our hospital. A total of 11 patients who underwent POEM for esophageal achalasia (n = 10) and jackhammer esophagus (n = 1) were included. Procedural success, defined as the completion of an esophageal and gastric myotomy, was 100%. Clinical success, defined as an Eckardt score of 3 or less, without the use of additional treatments at 2 months, was 100%. The median Eckardt score significantly decreased after the POEM (baseline vs. 2 months after POEM; 7 (2–8) vs. 0 (0–1), p < 0.01). In the second and third years, the cumulative treatment effect maintenance rate was 88.9%. All patients taking antithrombotic agents had safe operations with the temporary discontinuation of these agents. There were four adverse events (two pneumoperitoneum, one mucosal injury, and one pneumonia), all of which improved with fasting or antibiotics. In conclusion, POEM is an effective and safe treatment for esophageal achalasia and achalasia-related diseases in patients aged 75 years and over.
Keywords: elderly people; esophageal achalasia; gastroesophageal reflux disease; jackhammer esophagus; peroral endoscopic myotomy elderly people; esophageal achalasia; gastroesophageal reflux disease; jackhammer esophagus; peroral endoscopic myotomy

Share and Cite

MDPI and ACS Style

Nakamura, J.; Hikichi, T.; Hashimoto, M.; Takasumi, M.; Kato, T.; Kobashi, R.; Yanagita, T.; Suzuki, R.; Sugimoto, M.; Sato, Y.; et al. Efficacy and Safety of Peroral Endoscopic Myotomy for Esophageal Achalasia and Achalasia-Related Diseases in Patients Aged 75 Years and Over. Healthcare 2021, 9, 1668. https://doi.org/10.3390/healthcare9121668

AMA Style

Nakamura J, Hikichi T, Hashimoto M, Takasumi M, Kato T, Kobashi R, Yanagita T, Suzuki R, Sugimoto M, Sato Y, et al. Efficacy and Safety of Peroral Endoscopic Myotomy for Esophageal Achalasia and Achalasia-Related Diseases in Patients Aged 75 Years and Over. Healthcare. 2021; 9(12):1668. https://doi.org/10.3390/healthcare9121668

Chicago/Turabian Style

Nakamura, Jun, Takuto Hikichi, Minami Hashimoto, Mika Takasumi, Tsunetaka Kato, Ryoichiro Kobashi, Takumi Yanagita, Rei Suzuki, Mitsuru Sugimoto, Yuki Sato, and et al. 2021. "Efficacy and Safety of Peroral Endoscopic Myotomy for Esophageal Achalasia and Achalasia-Related Diseases in Patients Aged 75 Years and Over" Healthcare 9, no. 12: 1668. https://doi.org/10.3390/healthcare9121668

APA Style

Nakamura, J., Hikichi, T., Hashimoto, M., Takasumi, M., Kato, T., Kobashi, R., Yanagita, T., Suzuki, R., Sugimoto, M., Sato, Y., Irie, H., Takagi, T., Kobayakawa, M., & Ohira, H. (2021). Efficacy and Safety of Peroral Endoscopic Myotomy for Esophageal Achalasia and Achalasia-Related Diseases in Patients Aged 75 Years and Over. Healthcare, 9(12), 1668. https://doi.org/10.3390/healthcare9121668

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop