Phytochemical Constitution, Anti-Inflammation, Anti-Androgen, and Hair Growth-Promoting Potential of Shallot (Allium ascalonicum L.) Extract
Abstract
:1. Introduction
2. Results
2.1. Extraction Yield and Bioactive Compound Estimation
2.2. Cell Viability
2.3. Anti-Inflammatory Activity
2.4. Effect of Shallot Extract on Expressions of Genes Associated with Androgenetic Alopecia
3. Discussion
4. Materials and Methods
4.1. Preparation of Extract
4.2. Phytochemical Estimations
4.2.1. Total Phenolic Content
4.2.2. Total Flavonoid Content
4.2.3. Total Polysaccharide Content
4.2.4. Total Protein Content
4.3. Determination of Phenolic Compounds by Liquid Chromatography–Mass Spectrometry (LC-MS)
4.4. Cell Viability Assay
4.5. Anti-Inflammatory Activity
4.6. Semi-Quantitative Reverse Transcription and Polymerase Chain Reaction
4.7. Statistical Analysis
5. Conclusions
Author Contributions
Funding
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Bioactive Compounds | Content | |
---|---|---|
Total polysaccharide content | 0.90 ± 0.06 | mg D-glucose/g |
Total protein content | 1.01 ± 0.04 | mg BSAE/g |
Total phenolic content | 4.69 ± 0.42 | mg GAE/g |
Total flavonoid content | <0.003 | mg EGCGE/g |
Phenolic compounds | ||
p-Coumaric acid | 1.091 ± 0.011 | mg/g |
Quercetin | 0.029 ± 0.002 | mg/g |
Rosmarinic acid | 0.234 ± 0.007 | mg/g |
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Ruksiriwanich, W.; Khantham, C.; Muangsanguan, A.; Chittasupho, C.; Rachtanapun, P.; Jantanasakulwong, K.; Phimolsiripol, Y.; Sommano, S.R.; Sringarm, K.; Ferrer, E.; et al. Phytochemical Constitution, Anti-Inflammation, Anti-Androgen, and Hair Growth-Promoting Potential of Shallot (Allium ascalonicum L.) Extract. Plants 2022, 11, 1499. https://doi.org/10.3390/plants11111499
Ruksiriwanich W, Khantham C, Muangsanguan A, Chittasupho C, Rachtanapun P, Jantanasakulwong K, Phimolsiripol Y, Sommano SR, Sringarm K, Ferrer E, et al. Phytochemical Constitution, Anti-Inflammation, Anti-Androgen, and Hair Growth-Promoting Potential of Shallot (Allium ascalonicum L.) Extract. Plants. 2022; 11(11):1499. https://doi.org/10.3390/plants11111499
Chicago/Turabian StyleRuksiriwanich, Warintorn, Chiranan Khantham, Anurak Muangsanguan, Chuda Chittasupho, Pornchai Rachtanapun, Kittisak Jantanasakulwong, Yuthana Phimolsiripol, Sarana Rose Sommano, Korawan Sringarm, Emilia Ferrer, and et al. 2022. "Phytochemical Constitution, Anti-Inflammation, Anti-Androgen, and Hair Growth-Promoting Potential of Shallot (Allium ascalonicum L.) Extract" Plants 11, no. 11: 1499. https://doi.org/10.3390/plants11111499