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Open AccessReview

Fructans as Immunomodulatory and Antiviral Agents: The Case of Echinacea

1
Laboratory of Molecular Plant Biology, KU Leuven, 3001 Leuven, Belgium
2
Institute for Plant Biotechnology, Department of Genetics, Faculty of AgriSciences, Stellenbosch University, Matieland 7602, South Africa
*
Author to whom correspondence should be addressed.
Equally contributing senior authors.
Biomolecules 2019, 9(10), 615; https://doi.org/10.3390/biom9100615
Received: 19 September 2019 / Revised: 11 October 2019 / Accepted: 14 October 2019 / Published: 16 October 2019
Throughout history, medicinal purposes of plants have been studied, documented, and acknowledged as an integral part of human healthcare systems. The development of modern medicine still relies largely on this historical knowledge of the use and preparation of plants and their extracts. Further research into the human microbiome highlights the interaction between immunomodulatory responses and plant-derived, prebiotic compounds. One such group of compounds includes the inulin-type fructans (ITFs), which may also act as signaling molecules and antioxidants. These multifunctional compounds occur in a small proportion of plants, many of which have recognized medicinal properties. Echinacea is a well-known medicinal plant and products derived from it are sold globally for its cold- and flu-preventative and general health-promoting properties. Despite the well-documented phytochemical profile of Echinacea plants and products, little research has looked into the possible role of ITFs in these products. This review aims to highlight the occurrence of ITFs in Echinacea derived formulations and the potential role they play in immunomodulation. View Full-Text
Keywords: antioxidants; Echinacea; fructans; immunomodulation; prebiotics; herbal medicine antioxidants; Echinacea; fructans; immunomodulation; prebiotics; herbal medicine
MDPI and ACS Style

Dobrange, E.; Peshev, D.; Loedolff, B.; Van den Ende, W. Fructans as Immunomodulatory and Antiviral Agents: The Case of Echinacea. Biomolecules 2019, 9, 615. https://doi.org/10.3390/biom9100615

AMA Style

Dobrange E, Peshev D, Loedolff B, Van den Ende W. Fructans as Immunomodulatory and Antiviral Agents: The Case of Echinacea. Biomolecules. 2019; 9(10):615. https://doi.org/10.3390/biom9100615

Chicago/Turabian Style

Dobrange, Erin; Peshev, Darin; Loedolff, Bianke; Van den Ende, Wim. 2019. "Fructans as Immunomodulatory and Antiviral Agents: The Case of Echinacea" Biomolecules 9, no. 10: 615. https://doi.org/10.3390/biom9100615

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Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

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