Next Article in Journal
Matrix Metalloproteinases and Arterial Hypertension: Role of Oxidative Stress and Nitric Oxide in Vascular Functional and Structural Alterations
Next Article in Special Issue
Immunohistochemical Analysis of the Expression of Adhesion Proteins: TNS1, TNS2 and TNS3 in Correlation with Clinicopathological Parameters in Gastric Cancer
Previous Article in Journal
GPCR-Based Bioactive Peptide Screening Using Phage-Displayed Peptides and an Insect Cell System for Insecticide Discovery
Previous Article in Special Issue
3-Hydroxybutyrate as a Metabolite and a Signal Molecule Regulating Processes of Living Organisms
 
 
Review

Cation Transporters of Candida albicans—New Targets to Fight Candidiasis?

1
Moscow Institute of Physics and Technology, Institutskiy Pereulok, 9, 141700 Dolgoprudny, Moscow Oblast, Russia
2
Joint Institute for Nuclear Research, 141980 Dubna, Moscow Oblast, Russia
3
Groningen Biomolecular & Biosciences Institute, University of Groningen, 9747 AG Groningen, The Netherlands
*
Authors to whom correspondence should be addressed.
Biomolecules 2021, 11(4), 584; https://doi.org/10.3390/biom11040584
Received: 5 April 2021 / Accepted: 14 April 2021 / Published: 16 April 2021
(This article belongs to the Collection Feature Papers in Biochemistry)
Candidiasis is the wide-spread fungal infection caused by numerous strains of yeast, with the prevalence of Candida albicans. The current treatment of candidiasis is becoming rather ineffective and costly owing to the emergence of resistant strains; hence, the exploration of new possible drug targets is necessary. The most promising route is the development of novel antibiotics targeting this pathogen. In this review, we summarize such candidates found in C. albicans and those involved in the transport of (metal) cations, as the latter are essential for numerous processes within the cell; hence, disruption of their fluxes can be fatal for C. albicans. View Full-Text
Keywords: pathogen; candida; cation transporters; drug target; structure; structural biology pathogen; candida; cation transporters; drug target; structure; structural biology
Show Figures

Figure 1

MDPI and ACS Style

Volkova, M.; Atamas, A.; Tsarenko, A.; Rogachev, A.; Guskov, A. Cation Transporters of Candida albicans—New Targets to Fight Candidiasis? Biomolecules 2021, 11, 584. https://doi.org/10.3390/biom11040584

AMA Style

Volkova M, Atamas A, Tsarenko A, Rogachev A, Guskov A. Cation Transporters of Candida albicans—New Targets to Fight Candidiasis? Biomolecules. 2021; 11(4):584. https://doi.org/10.3390/biom11040584

Chicago/Turabian Style

Volkova, Marina, Anastasia Atamas, Alexey Tsarenko, Andrey Rogachev, and Albert Guskov. 2021. "Cation Transporters of Candida albicans—New Targets to Fight Candidiasis?" Biomolecules 11, no. 4: 584. https://doi.org/10.3390/biom11040584

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop