Next Article in Journal
Multifaceted Protective Role of Glucosamine against Osteoarthritis: Review of Its Molecular Mechanisms
Next Article in Special Issue
New Insights into Advanced Drug Delivery and Absorption Systems
Previous Article in Journal
The Optimization of Gel Preparations Using the Active Compounds of Arabica Coffee Ground Nanoparticles
Previous Article in Special Issue
Recent Approaches for Solid Dose Vaccine Delivery
 
Search for Articles:
Title / Keyword
Author / Affiliation
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
Journals
Sci. Pharm.
Volume 87
Issue 4
10.3390/scipharm87040033
scipharm-logo
Submit to this Journal Review for this Journal Edit a Special Issue
► Article Menu

Article Menu

share announcement thumb_up
...
textsms
...
Open AccessReview

Cyclodextrins in Drug Delivery Systems and Their Effects on Biological Barriers

by
Ádám Haimhoffer
1,2,†,
Ágnes Rusznyák
1,2,†,
Katalin Réti-Nagy
1,
Gábor Vasvári
1,2,
Judit Váradi
1,
Miklós Vecsernyés
1,
Ildikó Bácskay
1,
Pálma Fehér
1,
Zoltán Ujhelyi
1 and
Ferenc Fenyvesi
1,*
1
Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, Nagyerdei St. 98, H-4032 Debrecen, Hungary
2
Doctoral School of Pharmaceutical Sciences, University of Debrecen, H-4032 Debrecen, Hungary
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Sci. Pharm. 2019, 87(4), 33; https://doi.org/10.3390/scipharm87040033
Received: 24 September 2019 / Revised: 3 November 2019 / Accepted: 13 November 2019 / Published: 20 November 2019
(This article belongs to the Special Issue New Insights into Drug Delivery and Absorption)
View Full-Text Download PDF
Browse Figures

Abstract

Cyclodextrins are widely used excipients, composed of glucopyranose units with a cyclic structure. One of their most important properties, is that their inner cavity is hydrophobic, while their surface is hydrophilic. This enables them for the complex formation with lipophilic molecules. They have several applications in the pharmaceutical field like solubility enhancers or the building blocks of larger drug delivery systems. On the other hand, they have numerous effects on cells or biological barriers. In this review the most important properties of cyclodextrins and cyclodextrin-based drug delivery systems are summarized with special focus on their biological activity. View Full-Text
Keywords: cyclodextrins; drug delivery systems; biological barriers; nanopharmaceutics cyclodextrins; drug delivery systems; biological barriers; nanopharmaceutics
►▼ Show Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
SciFeed

Share and Cite

MDPI and ACS Style

Haimhoffer, Á.; Rusznyák, Á.; Réti-Nagy, K.; Vasvári, G.; Váradi, J.; Vecsernyés, M.; Bácskay, I.; Fehér, P.; Ujhelyi, Z.; Fenyvesi, F. Cyclodextrins in Drug Delivery Systems and Their Effects on Biological Barriers. Sci. Pharm. 2019, 87, 33. https://doi.org/10.3390/scipharm87040033

AMA Style

Haimhoffer Á, Rusznyák Á, Réti-Nagy K, Vasvári G, Váradi J, Vecsernyés M, Bácskay I, Fehér P, Ujhelyi Z, Fenyvesi F. Cyclodextrins in Drug Delivery Systems and Their Effects on Biological Barriers. Scientia Pharmaceutica. 2019; 87(4):33. https://doi.org/10.3390/scipharm87040033

Chicago/Turabian Style

Haimhoffer, Ádám; Rusznyák, Ágnes; Réti-Nagy, Katalin; Vasvári, Gábor; Váradi, Judit; Vecsernyés, Miklós; Bácskay, Ildikó; Fehér, Pálma; Ujhelyi, Zoltán; Fenyvesi, Ferenc. 2019. "Cyclodextrins in Drug Delivery Systems and Their Effects on Biological Barriers" Sci. Pharm. 87, no. 4: 33. https://doi.org/10.3390/scipharm87040033

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Map by Country/Region

1
Back to TopTop