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Recent Approaches for Solid Dose Vaccine Delivery

Department of Pharmacy, University of Asia Pacific, Dhaka 1205, Bangladesh
Department of Pharmaceutical Technology, University of Dhaka, Dhaka 1000, Bangladesh
Department of Chemical Engineering, Loughborough University, Loughborough LE11 3TU, UK
Author to whom correspondence should be addressed.
Sci. Pharm. 2019, 87(4), 27;
Received: 10 August 2019 / Revised: 12 September 2019 / Accepted: 18 September 2019 / Published: 14 October 2019
(This article belongs to the Special Issue New Insights into Drug Delivery and Absorption)
Recent studies on vaccine delivery systems are exploring the possibility of replacing liquid vaccines with solid dose vaccines due to the many advantages that solid dose vaccines can offer. These include the prospect of a needle-free vaccine delivery system leading to better patient compliance, cold chain storage, less-trained vaccinators and fewer chances for needle stick injury hazards. Some studies also indicate that vaccines in a solid dosage form can result in a higher level of immunogenicity compared to the liquid form, thus providing a dose-sparing effect. This review outlines the different approaches in solid vaccine delivery using various routes of administration including, oral, pulmonary, intranasal, buccal, sublingual, and transdermal routes. The various techniques and their current advancements will provide a knowledge base for future work to be carried out in this arena. View Full-Text
Keywords: vaccine; solid dose; dose-sparing; microneedle vaccine; solid dose; dose-sparing; microneedle
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MDPI and ACS Style

Jahan, N.; Archie, S.R.; Shoyaib, A.A.; Kabir, N.; Cheung, K. Recent Approaches for Solid Dose Vaccine Delivery. Sci. Pharm. 2019, 87, 27.

AMA Style

Jahan N, Archie SR, Shoyaib AA, Kabir N, Cheung K. Recent Approaches for Solid Dose Vaccine Delivery. Scientia Pharmaceutica. 2019; 87(4):27.

Chicago/Turabian Style

Jahan, Nishat, Sabrina R. Archie, Abdullah A. Shoyaib, Nadia Kabir, and Karmen Cheung. 2019. "Recent Approaches for Solid Dose Vaccine Delivery" Scientia Pharmaceutica 87, no. 4: 27.

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