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Evaluation of the Soothing and Protective Properties of a Lignin Hydrolyzate

Sinerga Group, Via della Pacciarna 67, 21050 Gorla Maggiore, (VA), Italy
Sinerga SPA, Via della Pacciarna 67, 21050 Gorla Maggiore, (VA), Italy
Rigano Laboratories Srl, 20125 Milan, Italy
Istituto Dermatologico S. Maria e S. Gallicano, IRRCS Via Chianesi 53, 00144 Roma, Italy
Authors to whom correspondence should be addressed.
Cosmetics 2019, 6(3), 38;
Received: 23 May 2019 / Revised: 20 June 2019 / Accepted: 26 June 2019 / Published: 3 July 2019
(This article belongs to the Special Issue Cosmetics: Feature Papers)
PDF [1159 KB, uploaded 3 July 2019]
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Lignins have shown remarkable antioxidant properties; acting as “scavengers” of free radicals physiologically produced by cell metabolisms; and exerting a protective action caused by the strong ability of these molecules to absorb UV radiation. Through preliminary Molecular Modeling studies and experimental studies in vivo and in vitro, a lignin hydrolysate compound has been shown to be an extremely versatile active ingredient, presenting soothing, anti-inflammatory, anti-itch, anti-oxidant, anti-aging and anti-pollution properties. The possible fields of application are therefore multiple; making this lignin hydrolysate a particularly interesting ingredient for topical dermatological compositions in the treatment of various skin disorders such as inflammation, edema, swelling, rash, redness, itching, chrono- and photo-induced skin aging. These manifestations are also the basis of more or less serious skin problems, making lignin hydrolysate capable of being used in cosmetic products for the eternal challenge of fighting skin aging, but also in medical devices that can be used to fight more painful and annoying symptoms, like those caused by dermatitis or psoriasis. View Full-Text
Keywords: lignin; polyphenols; skin disorders; dermatitis; psoriasis lignin; polyphenols; skin disorders; dermatitis; psoriasis

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Greco, L.; Ullo, S.; Rigano, L.; Fontana, M.; Berardesca, E. Evaluation of the Soothing and Protective Properties of a Lignin Hydrolyzate. Cosmetics 2019, 6, 38.

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