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Open AccessArticle

Aluminum Templates of Different Sizes with Micro-, Nano- and Micro/Nano-Structures for Cell Culture

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Division of Oral and Maxillofacial Surgery, Department of Dentistry, Taipei Medical University Hospital, Taipei 10617, Taiwan
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Department of Mechanical Engineering, National Taiwan University, Taipei 10617, Taiwan
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School of Dental Technology, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan
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Department of Dentistry, Taipei Medical University Hospital, Taipei 110, Taiwan
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Department of Business Administration, Takming University of Science and Technology, Taipei 114, Taiwan
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Research Center for Biomedical Devices, Taipei Medical University, Taipei 110, Taiwan
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Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 106, Taiwan
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Division of Endodontic, Department of Dentistry, Taipei Medical University Hospital, Taipei 10617, Taiwan
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Division of Family and Operative Dentistry, Department of Dentistry, Taipei Medical University Hospital, Taipei 10617, Taiwan
*
Author to whom correspondence should be addressed.
Academic Editor: Saber AminYavari
Coatings 2017, 7(11), 179; https://doi.org/10.3390/coatings7110179
Received: 23 August 2017 / Revised: 19 October 2017 / Accepted: 20 October 2017 / Published: 26 October 2017
(This article belongs to the Special Issue Surface Engineering of Biomaterials)
This study investigates the results of cell cultures on aluminum (Al) templates with flat-structures, micro-structures, nano-structures and micro/nano-structures. An Al template with flat-structure was obtained by electrolytic polishing; an Al template with micro-structure was obtained by micro-powder blasting; an Al template with nano-structure was obtained by aluminum anodization; and an Al template with micro/nano-structure was obtained by micro-powder blasting and then anodization. Osteoblast-like cells were cultured on aluminum templates with various structures. The microculture tetrazolium test assay was utilized to assess the adhesion, elongation, and proliferation behaviors of cultured osteoblast-like cells on aluminum templates with flat-structures, micro-structures, nano-structures, and micro/nano-structures. The results showed that the surface characterization of micro/nano-structure of aluminum templates had superhydrophilic property, and these also revealed that an aluminum template with micro/nano-structure could provide the most suitable growth situation for cell culture. View Full-Text
Keywords: surface modification; micro-powder blasting; aluminum anodization; micro/nano-structure; cell culture surface modification; micro-powder blasting; aluminum anodization; micro/nano-structure; cell culture
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Yen, M.-L.; Hsiao, H.-M.; Huang, C.-F.; Lin, Y.; Shen, Y.-K.; Tsai, Y.-L.; Chang, C.-W.; Yen, H.-J.; Lu, Y.-J.; Kuo, Y.-W. Aluminum Templates of Different Sizes with Micro-, Nano- and Micro/Nano-Structures for Cell Culture. Coatings 2017, 7, 179.

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