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Urinary Catheter Coating Modifications: The Race against Catheter-Associated Infections

Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA
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Author to whom correspondence should be addressed.
Coatings 2020, 10(1), 23; https://doi.org/10.3390/coatings10010023
Received: 14 November 2019 / Revised: 21 December 2019 / Accepted: 26 December 2019 / Published: 29 December 2019
(This article belongs to the Special Issue Recent Developments in Antibacterial and/or Antifouling Surfaces)
Urinary catheters are common medical devices, whose main function is to drain the bladder. Although they improve patients’ quality of life, catheter placement predisposes the patient to develop a catheter-associated urinary tract infection (CAUTI). The catheter is used by pathogens as a platform for colonization and biofilm formation, leading to bacteriuria and increasing the risk of developing secondary bloodstream infections. In an effort to prevent microbial colonization, several catheter modifications have been made ranging from introduction of antimicrobial compounds to antifouling coatings. In this review, we discuss the effectiveness of different coatings in preventing catheter colonization in vitro and in vivo, the challenges in fighting CAUTIs, and novel approaches targeting host–catheter–microbe interactions. View Full-Text
Keywords: CAUTI; antimicrobial compounds; coatings; urinary catheters; microbial; surface modifications; biofilm CAUTI; antimicrobial compounds; coatings; urinary catheters; microbial; surface modifications; biofilm
MDPI and ACS Style

Andersen, M.J.; Flores-Mireles, A.L. Urinary Catheter Coating Modifications: The Race against Catheter-Associated Infections. Coatings 2020, 10, 23.

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