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Open AccessFeature PaperReview

Antibacterial Coatings for Improving the Performance of Biomaterials

i+Med S. Coop, Parque Tecnológico de Alava. Albert Einstein 15, nave 15, 01510 Miñano, Spain
Macromolecular Chemistry Group (LABQUIMAC), Department of Physical Chemistry, Faculty of Science and Technology, University of the Basque Country, UPV/EHU, Barrio Sarriena, s/n 48940 Leioa, Spain
BCMaterials, Basque Center for Materials, Applications and Nanostructures, UPV/EHU Science Park, 48940 Leioa, Spain
Author to whom correspondence should be addressed.
Coatings 2020, 10(2), 139;
Received: 19 December 2019 / Revised: 21 January 2020 / Accepted: 30 January 2020 / Published: 4 February 2020
(This article belongs to the Special Issue Recent Developments in Antibacterial and/or Antifouling Surfaces)
Biomedical devices have become essential in the health care. Every day, an enormous number of these devices are used or implanted in humans. In this context, the bacterial contamination that could be developed in implanted devices is critical since it is estimated that infections kill more people than other medical causes. Commonly, these infections are treated with antibiotics, but the biofilm formation on implant surfaces could significantly reduce the effectiveness of these antibiotics since bacteria inside the biofilm is protected from the drug. In some cases, a complete removal of the implant is necessary in order to overcome the infection. In this context, antibacterial coatings are considered an excellent strategy to avoid biofilm formation and, therefore, mitigate the derived complications. In this review, the main biomaterials used in biomedical devices, the mechanism of biofilm formation, and the main strategies for the development of antibacterial coatings, are reviewed. Finally, the main polymer-based strategies to develop antibacterial coatings are summarized, with the aim of these coatings being to avoid the bacteria proliferation by controlling the antibacterial mechanisms involved and enhancing long-term stability. View Full-Text
Keywords: antibacterial coatings; contact killing; active surfaces antibacterial coatings; contact killing; active surfaces
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Olmo, J. .-D.; Ruiz-Rubio, L.; Pérez-Alvarez, L.; Sáez-Martínez, V.; Vilas-Vilela, J.L. Antibacterial Coatings for Improving the Performance of Biomaterials. Coatings 2020, 10, 139.

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