Next Article in Journal
Surgical Nuances to Reduce and Manage Cerebrospinal Fluid Leaks after Microvascular Decompression
Previous Article in Journal
Strengthened Default Mode Network Activation During Delay Discounting in Adolescents with Anorexia Nervosa After Partial Weight Restoration: A Longitudinal fMRI Study
Previous Article in Special Issue
Treatment of Obstructive Sleep Apnea in Children: Handling the Unknown with Precision
Open AccessReview

Sleep Disordered Breathing in Hypertrophic Cardiomyopathy—Current State and Future Directions

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA
Philadelphia Heart Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Division of Cardiology, Royal Papworth Hospital, Cambridge CB2 0AY, UK
Author to whom correspondence should be addressed.
Both authors contributed equally to the manuscript.
J. Clin. Med. 2020, 9(4), 901;
Received: 17 February 2020 / Revised: 18 March 2020 / Accepted: 23 March 2020 / Published: 25 March 2020
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy and sleep disordered breathing (SDB) is a treatable risk factor that has been seen to occur concurrently, and is known to propagate mortality and morbidity in a number of cardiovascular disease states including heart failure, and indeed hypertrophic cardiomyopathy. In this review, we summarize past studies that explored the simultaneous occurrence of HCM and SDB, and the pathophysiology of SDB in relation to heart failure, arrhythmias, cardiac ischemia and pulmonary hypertension in HCM. The current therapeutic modalities, with the effect of obstructive sleep apnea (OSA) treatment on HCM, are then discussed along with potential future directions. View Full-Text
Keywords: Sleep apnea; hypertrophic cardiomyopathy; sleep-disordered breathing Sleep apnea; hypertrophic cardiomyopathy; sleep-disordered breathing
Show Figures

Figure 1

MDPI and ACS Style

Venkataraman, S.; Karim, S.; Rajendran, A.; Chahal, C.A.A.; Somers, V.K. Sleep Disordered Breathing in Hypertrophic Cardiomyopathy—Current State and Future Directions. J. Clin. Med. 2020, 9, 901.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop