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Open AccessArticle

Electrochemical Disinfection of Experimentally Infected Teeth by Boron-Doped Diamond Electrode Treatment

1
Division of Ultra-Hard Coatings, Department of Material Sciences, University of Erlangen-Nuremberg, 91058 Erlangen, Germany
2
Microbiology Division, Department of Biology, University of Erlangen-Nuremberg, 91058 Erlangen, Germany
3
Department of Material Sciences, University of Erlangen-Nuremberg, 91058 Erlangen, Germany
4
Microbiology Division, Department of Biology, University of Erlangen-Nuremberg, 91058 Erlangen, Germany
5
Department of Prosthodontics, Saarland University, 66421 Homburg/Saar, Germany
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
J. Clin. Med. 2019, 8(12), 2037; https://doi.org/10.3390/jcm8122037
Received: 28 October 2019 / Revised: 15 November 2019 / Accepted: 19 November 2019 / Published: 21 November 2019
(This article belongs to the Special Issue New Ways to Disinfect and Fill Dental Hard Tissues)
Disinfection and prevention of re-infection are the decisive treatment steps in endodontic therapy. In this study, boron-doped diamond (BDD) electrodes have been fabricated and used for disinfecting the root canals of extracted human teeth, which had been covered with bacterial biofilms formed by Bacillus subtilis and Staphylococcus epidermidis. The growth of B. subtilis could be successfully impaired, achieving a complete disinfection after 8.5 min treatment time with the success of disinfection depending on the insertion depth of the electrode in the root canal. S. epidermidis could completely be removed after 3.5 min treatment time. A clinically applicable electrode array led to complete disinfection after treatment times of 10 min for S. epidermidis and 25 min for B. subtilis. BDD electrode application allowed for the improved disinfection of root canals and dentin tubules based on a continuous production of reactive oxygen species and their enhanced penetration of dentin tubules most likely due the formation of a continuous stream of small gas bubbles. The treatment times that are required here will be shortened in clinical application, as mechanical shaping of the canal system would precede the disinfection process.
Keywords: antimicrobial treatment; dentin tubules; electrochemical disinfection; endodontics; irrigating solutions; root canal antimicrobial treatment; dentin tubules; electrochemical disinfection; endodontics; irrigating solutions; root canal
MDPI and ACS Style

Böhm, A.-L.; Koch, M.; Rosiwal, S.; Burkovski, A.; Karl, M.; Grobecker-Karl, T. Electrochemical Disinfection of Experimentally Infected Teeth by Boron-Doped Diamond Electrode Treatment. J. Clin. Med. 2019, 8, 2037.

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