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J. Clin. Med. 2019, 8(1), 27; https://doi.org/10.3390/jcm8010027

Comprehensive Lung Function Assessment Does not Allow to Infer Response to Pulmonary Rehabilitation in Patients with COPD

1
CIRO+, center of expertise for chronic organ failure, 6085 NM Horn, The Netherlands
2
NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, 6229 ER Maastricht, The Netherlands
3
Department of Respiratory Medicine, Maastricht University Medical Centre+, 6229 HX Maastricht, The Netherlands
4
Viscovery Software GmbH, 1130 Vienna, Austria
*
Author to whom correspondence should be addressed.
Received: 19 November 2018 / Revised: 15 December 2018 / Accepted: 22 December 2018 / Published: 27 December 2018
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Abstract

The degree of lung function is frequently used as referral criterion for pulmonary rehabilitation. The efficacy of pulmonary rehabilitation was assessed in 518 chronic obstructive pulmonary disease (COPD) patients, after clustering based on a comprehensive pre-rehabilitation lung function assessment. Mean improvements in dyspnea, exercise performance, health status, mood status and problematic activities of daily life after pulmonary rehabilitation were mostly comparable between the seven clusters, despite significant differences in the degree of lung function. The current study demonstrates no significant relationship between the seven lung-function-based clusters and response to pulmonary rehabilitation. Therefore, baseline lung function cannot be used to identify those who will respond well to pulmonary rehabilitation, and moreover, cannot be used as a criterion for referral to pulmonary rehabilitation in patients with COPD. View Full-Text
Keywords: pulmonary rehabilitation; COPD; response pulmonary rehabilitation; COPD; response
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Augustin, I.M.L.; Wouters, E.F.M.; Houben-Wilke, S.; Gaffron, S.; Janssen, D.J.A.; Franssen, F.M.E.; Spruit, M.A. Comprehensive Lung Function Assessment Does not Allow to Infer Response to Pulmonary Rehabilitation in Patients with COPD. J. Clin. Med. 2019, 8, 27.

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