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Open AccessCase Report

An Unusual and Fatal Cause of Miliary Nodules on Chest Radiography

1
Department of Medicine, Jersey Shore University Medical Center, Hackensack Meridian Health, 1945 State Route 33, Neptune, NJ 07753, USA
2
Department of Pathology, Jersey Shore University Medical Center, Hackensack Meridian Health, 1945 State Route 33, Neptune, NJ 07753, USA
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2018, 7(7), 164; https://doi.org/10.3390/jcm7070164
Received: 31 May 2018 / Revised: 25 June 2018 / Accepted: 25 June 2018 / Published: 29 June 2018
(This article belongs to the Section Nuclear Medicine & Radiology)
Foreign body granulomatosis has many etiologies, including the injection of oral medications intravenously. The insoluble filler materials that are used in the medications can lodge in pulmonary arterioles and capillaries, which can trigger foreign body giant cell reaction, chronic inflammation, thrombosis, and fibrosis, resulting in pulmonary hypertension, progressive shortness of breath, and, potentially, fatal conditions. On imaging, this may present with multiple miliary mottling’s/nodules. The use of a bronchoscopy with biopsy can be an excellent way to establish a diagnosis in appropriate clinical settings. Here, we present a case of a 37-year-old old male found to have multiple miliary densities on imaging due to intravenous use of oral medication. View Full-Text
Keywords: foreign body granulomatosis; talc; microcrystalline cellulose; intravenous drug use foreign body granulomatosis; talc; microcrystalline cellulose; intravenous drug use
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Cheema, A.; Chaughtai, S.; Mazahir, U.; Roy, M.; Hossain, M.A. An Unusual and Fatal Cause of Miliary Nodules on Chest Radiography. J. Clin. Med. 2018, 7, 164.

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