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Review

Current Management and Treatment Paradigms of Gastroesophageal Reflux Disease following Sleeve Gastrectomy

by
Muaaz Masood
1,
Donald E. Low
2,
Shanley B. Deal
3 and
Richard A. Kozarek
1,4,*
1
Division of Gastroenterology and Hepatology, Center for Digestive Health, Virginia Mason Franciscan Health, Seattle, WA 98101, USA
2
Division of Thoracic Surgery, Center for Digestive Health, Virginia Mason Franciscan Health, Seattle, WA 98101, USA
3
Division of General and Bariatric Surgery, Center for Weight Management, Virginia Mason Franciscan Health, Seattle, WA 98101, USA
4
Center for Interventional Immunology, Benaroya Research Institute, Virginia Mason Franciscan Health, Seattle, WA 98101, USA
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2024, 13(5), 1246; https://doi.org/10.3390/jcm13051246
Submission received: 15 January 2024 / Revised: 16 February 2024 / Accepted: 19 February 2024 / Published: 22 February 2024
(This article belongs to the Special Issue Sleeve Gastrectomy: Risks, Outcomes, and Complications)
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Abstract

Obesity is associated with serious comorbidities and economic implications. Bariatric surgery, most commonly Roux-en-Y gastric bypass and sleeve gastrectomy, are effective options for weight loss and the improvement of obesity-related comorbidities. With the growing obesity epidemic, there has been a concomitant rise in bariatric surgeries, particularly in sleeve gastrectomy, which has been the most widely performed bariatric surgery since 2013. Gastroesophageal reflux disease (GERD) is highly prevalent in obese individuals, can significantly impact quality of life and may lead to serious complications. Obesity and GERD both improve with weight loss. However, as the incidence of sleeve gastrectomy rises, recent data have revealed a risk of exacerbation of pre-existing GERD or the development of de novo GERD following sleeve gastrectomy. We performed a detailed review of GERD post-sleeve gastrectomy, including its overall incidence, pathophysiology and current treatment paradigms.
Keywords: gastroesophageal; reflux; GERD; esophagitis; morbid; obesity; bariatric; gastric; sleeve; gastrectomy gastroesophageal; reflux; GERD; esophagitis; morbid; obesity; bariatric; gastric; sleeve; gastrectomy
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MDPI and ACS Style

Masood, M.; Low, D.E.; Deal, S.B.; Kozarek, R.A. Current Management and Treatment Paradigms of Gastroesophageal Reflux Disease following Sleeve Gastrectomy. J. Clin. Med. 2024, 13, 1246. https://doi.org/10.3390/jcm13051246

AMA Style

Masood M, Low DE, Deal SB, Kozarek RA. Current Management and Treatment Paradigms of Gastroesophageal Reflux Disease following Sleeve Gastrectomy. Journal of Clinical Medicine. 2024; 13(5):1246. https://doi.org/10.3390/jcm13051246

Chicago/Turabian Style

Masood, Muaaz, Donald E. Low, Shanley B. Deal, and Richard A. Kozarek. 2024. "Current Management and Treatment Paradigms of Gastroesophageal Reflux Disease following Sleeve Gastrectomy" Journal of Clinical Medicine 13, no. 5: 1246. https://doi.org/10.3390/jcm13051246

APA Style

Masood, M., Low, D. E., Deal, S. B., & Kozarek, R. A. (2024). Current Management and Treatment Paradigms of Gastroesophageal Reflux Disease following Sleeve Gastrectomy. Journal of Clinical Medicine, 13(5), 1246. https://doi.org/10.3390/jcm13051246

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