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Review

Characteristics and Detection Rate of SARS-CoV-2 in Alternative Sites and Specimens Pertaining to Dental Practice: An Evidence Summary

1
Department of Oral Biology, College of Dentistry, University of Illinois at Chicago, 801 S Paulina St, Chicago, IL 60612, USA
2
Department of Restorative Dentistry, University of Illinois at Chicago, Chicago, IL 60612, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Hans-Peter Howaldt
J. Clin. Med. 2021, 10(6), 1158; https://doi.org/10.3390/jcm10061158
Received: 6 February 2021 / Revised: 4 March 2021 / Accepted: 8 March 2021 / Published: 10 March 2021
(This article belongs to the Special Issue Impact of COVID-19 on the Dental Community)
Knowledge about the detection potential and detection rates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in various body fluids and sites is important for dentists since they, directly or indirectly, deal with many of these fluids/sites in their daily practices. In this study, we attempt to review the latest evidence and meta-analysis studies regarding the detection rate of SARS-CoV-2 in different body specimens and sites as well as the characteristics of these sample. The presence/detection of SARS-CoV-2 viral biomolecules (nucleic acid, antigens, antibody) in different clinical specimens depends greatly on the specimen type and timing of collection. These specimens/sites include nasopharynx, oropharynx, nose, saliva, sputum, bronchoalveolar lavage, stool, urine, ocular fluid, serum, plasma and whole blood. The relative detection rate of SARS-CoV-2 viral biomolecules in each of these specimens/sites is reviewed in detail within the text. The infectious potential of these specimens depends mainly on the time of specimen collection and the presence of live replicating viral particles. View Full-Text
Keywords: dentistry; RT-PCR testing; antigen; antibody; saliva; aerosols; body fluids; viral load; epidemiological monitoring; COVID-19 dentistry; RT-PCR testing; antigen; antibody; saliva; aerosols; body fluids; viral load; epidemiological monitoring; COVID-19
MDPI and ACS Style

Shirazi, S.; Stanford, C.M.; Cooper, L.F. Characteristics and Detection Rate of SARS-CoV-2 in Alternative Sites and Specimens Pertaining to Dental Practice: An Evidence Summary. J. Clin. Med. 2021, 10, 1158. https://doi.org/10.3390/jcm10061158

AMA Style

Shirazi S, Stanford CM, Cooper LF. Characteristics and Detection Rate of SARS-CoV-2 in Alternative Sites and Specimens Pertaining to Dental Practice: An Evidence Summary. Journal of Clinical Medicine. 2021; 10(6):1158. https://doi.org/10.3390/jcm10061158

Chicago/Turabian Style

Shirazi, Sajjad, Clark M. Stanford, and Lyndon F. Cooper 2021. "Characteristics and Detection Rate of SARS-CoV-2 in Alternative Sites and Specimens Pertaining to Dental Practice: An Evidence Summary" Journal of Clinical Medicine 10, no. 6: 1158. https://doi.org/10.3390/jcm10061158

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