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Volume 10
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10.3390/jcm10020268
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Open AccessReview

Could Chronic Idiopatic Intestinal Pseudo-Obstruction Be Related to Viral Infections?

by
Emanuele Sinagra
1,2,*,†,
Gaia Pellegatta
3,†,
Marcello Maida
4,
Francesca Rossi
1,
Giuseppe Conoscenti
1,
Socrate Pallio
5,
Rita Alloro
6,
Dario Raimondo
1 and
Andrea Anderloni
3
1
Gastroenterology and Endoscopy Unit, Fondazione Istituto San Raffaele-Giuseppe Giglio, Contrada Pietra Pollastra Pisciotto, 90015 Cefalù, Italy
2
Euro-Mediterranean Institute of Science and Technology (IEMEST), 90139 Palermo, Italy
3
Digestive Endoscopy Unit, Division of Gastroenterology, Humanitas Clinical and Research Center (IRCCS), 20089 Rozzano, Italy
4
Gastroenterology and Endoscopy Unit, S. Elia-Raimondi Hospital, 93100 Caltanissetta, Italy
5
Endoscopy Unit, University Hospital Policlinic G. Martino, 98125 Messina, Italy
6
Division of General and Oncologic Surgery, Department of Surgical, Oncological and Oral Sciences (DICHIRONS), University of Palermo, 90133 Palermo, Italy
*
Author to whom correspondence should be addressed.
†
Equal contribution.
J. Clin. Med. 2021, 10(2), 268; https://doi.org/10.3390/jcm10020268
Received: 30 November 2020 / Revised: 7 January 2021 / Accepted: 11 January 2021 / Published: 13 January 2021
(This article belongs to the Special Issue Enteric Nervous System: Neuropathic Gastrointestinal Motility)
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Abstract

Chronic idiopathic intestinal pseudo-obstruction (CIIPO) is a disease characterized by symptoms and signs of small bowel obstruction in the absence of displayable mechanical obstruction. Due to the known neuropathic capacity of several viruses, and their localization in the intestine, it has been hypothesized that such viruses could be involved in the pathogenesis of CIIPO. The most frequently involved viruses are John Cunningham virus, Herpesviridae, Flaviviruses, Epstein–Barr virus and Citomegalovirus. Therefore, the present narrative review aims to sum up some new perspectives in the etiology and pathophysiology of CIIPO. View Full-Text
Keywords: virus; chronic idiopathic intestinal pseudo-obstruction; gastrointestinal motility disorders virus; chronic idiopathic intestinal pseudo-obstruction; gastrointestinal motility disorders
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MDPI and ACS Style

Sinagra, E.; Pellegatta, G.; Maida, M.; Rossi, F.; Conoscenti, G.; Pallio, S.; Alloro, R.; Raimondo, D.; Anderloni, A. Could Chronic Idiopatic Intestinal Pseudo-Obstruction Be Related to Viral Infections? J. Clin. Med. 2021, 10, 268.

AMA Style

Sinagra E, Pellegatta G, Maida M, Rossi F, Conoscenti G, Pallio S, Alloro R, Raimondo D, Anderloni A. Could Chronic Idiopatic Intestinal Pseudo-Obstruction Be Related to Viral Infections? Journal of Clinical Medicine. 2021; 10(2):268.

Chicago/Turabian Style

Sinagra, Emanuele; Pellegatta, Gaia; Maida, Marcello; Rossi, Francesca; Conoscenti, Giuseppe; Pallio, Socrate; Alloro, Rita; Raimondo, Dario; Anderloni, Andrea. 2021. "Could Chronic Idiopatic Intestinal Pseudo-Obstruction Be Related to Viral Infections?" J. Clin. Med. 10, no. 2: 268.

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