IBS-Symptoms in IBD Patients—Manifestation of Concomitant or Different Entities
1
Department of Biochemistry, Medical University of Lodz, Mazowiecka 6/8, 92-215 Lodz, Poland
2
Department of General and Colorectal Surgery, Medical University of Lodz, Haller Square 1, 90-624 Lodz, Poland
3
Colon and Rectal Surgery Division, Humanitas Clinical and Research Center IRCCS, Rozzano, 20089 Milano, Italy
4
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, 20090 Milano, Italy
*
Author to whom correspondence should be addressed.
†
Authors equally contributed to this study.
J. Clin. Med. 2021, 10(1), 31; https://doi.org/10.3390/jcm10010031
Received: 4 November 2020
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Revised: 14 December 2020
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Accepted: 22 December 2020
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Published: 24 December 2020
(This article belongs to the Special Issue Enteric Nervous System: Neuropathic Gastrointestinal Motility)
Irritable bowel syndrome (IBS) is a functional heterogenous disease with a multifactorial pathogenesis. It is characterized by abdominal pain, discomfort, and alteration in gut motility. The occurrence of similar symptoms was observed in patients in clinical remission of inflammatory bowel diseases (IBD) that is Crohn’s disease (CD) and ulcerative colitis (UC), which pathogenesis is also not fully understood. Hence, arose the question if these symptoms are “true IBS” imposed on IBD, or is it a subclinical form of IBD or even pre-IBD? In this article, based on a narrative overview of the literature, we try to find an answer to this query by discussing the pathogenesis and overlaps between these conditions.
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Keywords:
irritable bowel syndrome; inflammatory bowel diseases; irritable bowel symptoms; remission; fecal calprotectin; inflammation; gut–brain axis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
MDPI and ACS Style
Szałwińska, P.; Włodarczyk, J.; Spinelli, A.; Fichna, J.; Włodarczyk, M. IBS-Symptoms in IBD Patients—Manifestation of Concomitant or Different Entities. J. Clin. Med. 2021, 10, 31. https://doi.org/10.3390/jcm10010031
AMA Style
Szałwińska P, Włodarczyk J, Spinelli A, Fichna J, Włodarczyk M. IBS-Symptoms in IBD Patients—Manifestation of Concomitant or Different Entities. Journal of Clinical Medicine. 2021; 10(1):31. https://doi.org/10.3390/jcm10010031
Chicago/Turabian StyleSzałwińska, Patrycja, Jakub Włodarczyk, Antonino Spinelli, Jakub Fichna, and Marcin Włodarczyk. 2021. "IBS-Symptoms in IBD Patients—Manifestation of Concomitant or Different Entities" Journal of Clinical Medicine 10, no. 1: 31. https://doi.org/10.3390/jcm10010031
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