Review Reports

Round 1

Reviewer 1 Report

Editing of the English language and style is very required.

Author Response

We have received the reviewers’ comment regarding the need to improve the language in this manuscript.  Although we were surprised by these comments, as the paper was written by native English-speaking medical writers, we understand that some sections could have been written clearer. To this end we have invited an independent, native English medical writer to fully edit and revise the manuscript once again.

If there are any further issues with the language, style or readability we would be grateful if specific examples could be provided.

We hope that you will find these additional changes satisfactory.

Kind regards,

On behalf of the co-authors,

Professor Thibaud Damy

Reviewer 2 Report

The paper need exstensive grammaticali and languge revision. Please refer the manuscript to a professional editing service. 
When I have a readable paper I can evaluate the scientific contenent of the paper

Author Response

We have received the reviewers’ comment regarding the need to improve the language in this manuscript.  Although we were surprised by these comments, as the paper was written by native English-speaking medical writers, we understand that some sections could have been written clearer. To this end we have invited an independent, native English medical writer to fully edit and revise the manuscript once again.

If there are any further issues with the language, style or readability we would be grateful if specific examples could be provided.

We hope that you will find these additional changes satisfactory.

Kind regards,

On behalf of the co-authors,

Professor Thibaud Damy