Models for Facilitated Transport Membranes: A Review
Dipartimento di Ingegneria Civile, Chimica, Ambientale e dei Materiali (DICAM), Università di Bologna, Via Terracini 28, 40131 Bologna, Italy
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Received: 9 December 2018 / Revised: 14 January 2019 / Accepted: 15 January 2019 / Published: 2 February 2019
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Facilitated transport membranes are particularly promising in different separations, as they are potentially able to overcome the trade-off behavior usually encountered in solution-diffusion membranes. The reaction activated transport is a process in which several mechanisms take place simultaneously, and requires a rigorous theoretical analysis, which unfortunately is often neglected in current studies more focused on material development. In this work, we selected and reviewed the main mathematical models introduced to describe mobile and fixed facilitated transport systems in steady state conditions, in order to provide the reader with an overview of the existing mathematical tools. An analytical solution to the mass transport problem cannot be achieved, even when considering simple reaction schemes such as that between oxygen (solute) and hemoglobin (carrier) (
), that was thoroughly studied by the first works dealing with this type of biological facilitated transport. Therefore, modeling studies provided approximate analytical solutions and comparison against experimental observations and exact numerical calculations. The derivation, the main assumptions, and approximations of such modeling approaches is briefly presented to assess their applicability, precision, and flexibility in describing and understanding mobile and fixed site carriers facilitated transport membranes. The goal is to establish which mathematical tools are more suitable to support and guide the development and design of new facilitated transport systems and materials. Among the models presented, in particular, those from Teramoto and from Morales-Cabrera et al. seem the more flexible and general ones for the mobile carrier case, while the formalization made by Noble and coauthors appears the most complete in the case of fixed site carrier membranes.
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MDPI and ACS Style
Rea, R.; De Angelis, M.G.; Baschetti, M.G. Models for Facilitated Transport Membranes: A Review. Membranes 2019, 9, 26.
Rea R, De Angelis MG, Baschetti MG. Models for Facilitated Transport Membranes: A Review. Membranes. 2019; 9(2):26.
Rea, Riccardo; De Angelis, Maria G.; Baschetti, Marco G. 2019. "Models for Facilitated Transport Membranes: A Review." Membranes 9, no. 2: 26.
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