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Decline of Anti-SARS-CoV-2 IgG Antibody Levels 6 Months after Complete BNT162b2 Vaccination in Healthcare Workers to Levels Observed Following the First Vaccine Dose
 
 
Article
Peer-Review Record

Monitoring of SARS-CoV-2 Specific Antibodies after Vaccination

Vaccines 2022, 10(2), 154; https://doi.org/10.3390/vaccines10020154
by Raquel Guiomar 1,†, Ana João Santos 2,†, Aryse Martins Melo 1,*,†, Inês Costa 1, Rita Matos 3, Ana Paula Rodrigues 2, Irina Kislaya 2, Anabela Santos Silva 4, Carla Roque 5, Carla Nunes 4, Joaquim Aguiar 4, Fátima Graça 4, Antônio Silva Graça 5 and Ausenda Machado 2
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Vaccines 2022, 10(2), 154; https://doi.org/10.3390/vaccines10020154
Submission received: 22 December 2021 / Accepted: 13 January 2022 / Published: 20 January 2022
(This article belongs to the Section COVID-19 Vaccines and Vaccination)

Round 1

Reviewer 1 Report

 The revised manuscript presents data on binding and neutralizing (achieved by surrogate ELISA assay) SARS-CoV-2 antibody levels in a cohort of 132 people in Portugal. These data are useful for understanding  the immune response after vaccination, and further proved that the antibody levels could be enhanced after second vaccine injection and decrease along the time after vaccination. The authors have answered my previous concern on testing neutralizing antibodies and I have no more suggestions.

Reviewer 2 Report

The quality of this paper has been improved compared to the previous version.

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