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Open AccessArticle

Colorimetric Technique for Antimony Detection Based on the Use of Gold Nanoparticles Conjugated with Poly-A Oligonucleotide

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A.N. Bach Institute of Biochemistry, Research Center of Biotechnology of the Russian Academy of Sciences, Leninsky prospect 33, 119071 Moscow, Russia
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Department of Physics, Hindustan College of Science and Technology, Distt.: Mathura U.P., Farah 281122, India
*
Author to whom correspondence should be addressed.
Appl. Sci. 2019, 9(22), 4782; https://doi.org/10.3390/app9224782
Received: 1 October 2019 / Revised: 31 October 2019 / Accepted: 6 November 2019 / Published: 8 November 2019
A simple and rapid positive–negative colorimetric approach to determine the presence of antimony ions based on the use of gold nanoparticles conjugated with oligonucleotide (poly-A sequence) is developed. Colorimetric measurements reveal that the aggregates of modified gold nanoparticles were afforded after adding antimony ions, thus changing the solution color from pink to blue. The results of aptamer’s interaction on the gold nanoparticle surface with the target analyte can be detected either by photometry or by the naked eye. The realized assay provides rapid (2 min), sensitive (detection limit 10 ng/mL), specific, and precise (variation coefficient less than 3.8%) detection of antimony (III) in drinking water. View Full-Text
Keywords: heavy metal analyses; gold nanoparticles; oligonucleotide; antimony; color change heavy metal analyses; gold nanoparticles; oligonucleotide; antimony; color change
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Berlina, A.N.; Komova, N.S.; Zherdev, A.V.; Gaur, M.S.; Dzantiev, B.B. Colorimetric Technique for Antimony Detection Based on the Use of Gold Nanoparticles Conjugated with Poly-A Oligonucleotide. Appl. Sci. 2019, 9, 4782.

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