Maxillary Sinusitis of Odontogenic Origin: Prevalence among 3D Imaging—A Retrospective Study

Round 1

Reviewer 1 Report

The presented paper follows the international guidelines regarding a scientific research, being well structured and documented.

The topic is clearly explained in the introduction part, higlighting the importance of a correct diagnosis of the odontogenic sinusitis in relation to the maxillary anatomy and potential causes of infection. The results are well described and presented using adequate visual instruments. In fig 4, the name of the patient should be removed.

Nevertheless, the topic is a rather well known one, thus the originality of the research is questionable. 

Out of the 33 reference titles, only 15 (less than half) are of the last 10 years, which I consider to be an aspect that could be improved. I suggest an improvement in this regard.

Author Response

 Dear reviewer,
Thank you for your comments. the following changes have been done according to your comments:
1- Patient's name has been removed from figure 4.
2- several recent articles were added to the references list and they include:

 
a)     Turfe, Z., Ahmad, A., Peterson, E.I. and Craig, J.R., 2019, December. Odontogenic sinusitis is a common cause of unilateral sinus disease with maxillary sinus opacification. In International Forum of Allergy & Rhinology (Vol. 9, No. 12, pp. 1515-1520).
b)    Allevi, F., Fadda, G.L., Rosso, C., Martino, F., Pipolo, C., Cavallo, G., Felisati, G. and Saibene, A.M., 2021. Diagnostic criteria for odontogenic sinusitis: a systematic review. American Journal of Rhinology & Allergy, 35(5), pp.713-721.
c)     Whyte, A. and Boeddinghaus, R., 2019. Imaging of odontogenic sinusitis. Clinical radiology, 74(7), pp.503-516.
d)    Garry, S., O'Riordan, I., James, D., Corbett, M., Barry, T. and Thornton, M., 2021. Odontogenic Sinusitis–Case Series and Review of Literature. The Journal of Laryngology & Otology, pp.1-18.
e)      Kuligowski, P.; Jaroń, A.; Preuss, O.; Gabrysz-Trybek, E.; Bladowska, J.; Trybek, G. Association between Odontogenic and Maxillary Sinus Conditions: A Retrospective Cone-Beam Computed Tomographic Study. J. Clin. Med. 2021, 10, 2849. https://doi.org/10.3390/jcm10132849
 
Allow me to thank you for your valuable comments.

Best wishes.
 

Reviewer 2 Report

The reference list of the manuscript contains 33 titles, and is without inappropriate self-citations. Five references are elder than 20 years. The manuscript is clear, with a good rate of novelty and significance. The manuscript present scientific resound and the design appropriate to test the hypothesis. The methods and software are clear described, with sufficient details to permit another researcher to reproduce the results. All aspects regarding the figures/tables/images are appropriate, and they are easy to interpret and understand. The presentation and the analyzed date are written in proper way. The presentation of the results are at high standard, with appropriate statistics. The results offer a development in the present knowledge, are significant, and are suitable interpreted.

If have only some comments and found some spelling mistakes:

• L11 --> The Aim ... --> The aim ...
• L37-39: What about dental implants? Allografts after sinus floor elevation?
• L143: compared --> Compared
• LL194-196: Could add the reported frequency of nasal septal deviation and maxillary sinusitis.
• Are there any cases with status after apical root resection?
• Did you find any impact of bony septs (Underwood septs?) in the maxillary sinus?
• I am surprised that the rate of thickening and periapical pathology of the third molar was the highest in their study. Please give the reader more information about this (e.g. status of impaction? )

Author Response

Dear reviewer,

Thank you for your comments. the following changes have been done according to your comments:

Several recent references were added with 3 of them published in 2021.

All spelling mistakes noted were corrected and a complete manuscript proofread has been carried out before resubmitting.

Effect of dental implants placement and use of bone grafts effect on development and progression of odontogenic sinusitis has been added with the relevant referencing.

A sentence noting that the sample did not contain any case with root resection has been added.

In regards to the nasal septum deviation relationship to odontogenic Sinusitis, unfortunately, it is not applicable to measure the correlation as the nasal septum deviation was not among the parameters investigated.

For the 3rd molars, the degree of impaction was not included in the data collected as the data was purely radiographic without any clinical aspect. however, when distance of root apex to sinus floor was measured there was no statistical significance difference between 3rd molars and other included teeth. the same goes for the root apex sinus floor perforation.

Allow me to thank you for your valuable comments.

Best wishes

Reviewer 3 Report

The abstract describes the study well. 
Key words are well chosen and reflect the study well. 
Introduction: introduces the reader to the topics covered in the article very well. Presents theoretical information about the issue well. 
The methodology of the study is well described, including a description of bioethics committee approval, inclusion and exclusion criteria, study group and control. 
Results are presented in an understandable manner
The discussion discusses the results well and relates them to contemporary literature
It would be worthwhile to enrich the study with the following literature item:
Kuligowski, P.; Jaroń, A.; Preuss, O.; Gabrysz-Trybek, E.; Bladowska, J.; Trybek, G. Association between Odontogenic and Maxillary Sinus Conditions: A Retrospective Cone-Beam Computed Tomographic Study. J. Clin. Med. 2021, 10, 2849. https://doi.org/10.3390/jcm10132849

Please describe the limitations of the study and future directions. 
Conclusions correspond with the purpose of the study. 

Author Response

Dear reviewer,

Thank you for your comments. the following changes have been done according to your comments:

The suggested reference was added within the relevant paragraph.

Limitations and future directions were added to the manuscript.

Allow me to thank you for your valuable comments.

Best wishes.