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Review

Nanotechnology Development for Formulating Essential Oils in Wound Dressing Materials to Promote the Wound-Healing Process: A Review

1
Elleva Pharma S.R.L. Via Pietro Castellino, 111, 80131 Naples, Italy
2
Department of Chemical, Materials and Industrial Production Engineering, University of Naples Federico II, 80138 Napoli, Italy
3
Center for Advanced Biomaterials for Healthcare, Istituto Italiano di Tecnologia ([email protected]), 80125 Naples, Italy
4
Fluid Dynamics of Complex Biosystems, School of Life Sciences Weihenstephan, Technical University of Munich, 85354 Freising, Germany
5
Institute for Polymers, Composites and Biomaterials (IPCB-CNR), Via Campi Flegrei 34, 80078 Pozzuoli, Italy
6
Research Institute on Terrestrial Ecosystems (IRET)—CNR, Via Pietro Castellino 111, 80131 Naples, Italy
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Won Ho Park
Appl. Sci. 2021, 11(4), 1713; https://doi.org/10.3390/app11041713
Received: 22 December 2020 / Revised: 2 February 2021 / Accepted: 5 February 2021 / Published: 14 February 2021
(This article belongs to the Special Issue Nanotechnology in Tissue Engineering)
Wound healing refers to the replacement of damaged tissue through strongly coordinated cellular events. The patient’s condition and different types of wounds complicate the already intricate healing process. Conventional wound dressing materials seem to be insufficient to facilitate and support this mechanism. Nanotechnology could provide the physicochemical properties and specific biological responses needed to promote the healing process. For nanoparticulate dressing design, growing interest has focused on natural biopolymers due to their biocompatibility and good adaptability to technological needs. Polysaccharides are the most common natural biopolymers used for wound-healing materials. In particular, alginate and chitosan polymers exhibit intrinsic antibacterial and anti-inflammatory effects, useful for guaranteeing efficient treatment. Recent studies highlight that several natural plant-derived molecules can influence healing stages. In particular, essential oils show excellent antibacterial, antifungal, antioxidant, and anti-inflammatory properties that can be amplified by combining them with nanotechnological strategies. This review summarizes recent studies concerning essential oils as active secondary compounds in polysaccharide-based wound dressings. View Full-Text
Keywords: polysaccharides; wound dressing; essential oils; nanotechnology; wound healing; antimicrobial; antioxidant polysaccharides; wound dressing; essential oils; nanotechnology; wound healing; antimicrobial; antioxidant
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MDPI and ACS Style

De Luca, I.; Pedram, P.; Moeini, A.; Cerruti, P.; Peluso, G.; Di Salle, A.; Germann, N. Nanotechnology Development for Formulating Essential Oils in Wound Dressing Materials to Promote the Wound-Healing Process: A Review. Appl. Sci. 2021, 11, 1713. https://doi.org/10.3390/app11041713

AMA Style

De Luca I, Pedram P, Moeini A, Cerruti P, Peluso G, Di Salle A, Germann N. Nanotechnology Development for Formulating Essential Oils in Wound Dressing Materials to Promote the Wound-Healing Process: A Review. Applied Sciences. 2021; 11(4):1713. https://doi.org/10.3390/app11041713

Chicago/Turabian Style

De Luca, Ilenia, Parisa Pedram, Arash Moeini, Pierfrancesco Cerruti, Gianfranco Peluso, Anna Di Salle, and Natalie Germann. 2021. "Nanotechnology Development for Formulating Essential Oils in Wound Dressing Materials to Promote the Wound-Healing Process: A Review" Applied Sciences 11, no. 4: 1713. https://doi.org/10.3390/app11041713

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