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Medical Sciences, Volume 7, Issue 5

May 2019 - 2 articles

Cover Story: Diaphragmatic dysfunction is a common cause of slow weaning in mechanically ventilated patients. The aim of our study was to evaluate the motion of the diaphragm in patients who were ventilated for a protracted period in comparison with healthy controls by using magnetic resonance imaging (MRI). The advantage of MRI lies in its capability of directly acquiring coronal and sagittal images of the entire diaphragm, which can reveal focal, unilateral, or global diaphragmatic motion abnormalities. By using MRI dynamic sequences, we found that the vertical displacement of both right and left hemi-diaphragms at various anatomical locations had different values in both controls and patients. The ventilator induced diaphragm dysfunction in our patients was regional as well as global. View this paper.

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Feature Paper
Article

5 Citations

3,324 Views

8 Pages

MRI Assessment of Global and Regional Diaphragmatic Motion in Critically Ill Patients Following Prolonged Ventilator Weaning

Khurram Saleem Khan,
James Meaney,
Ignacio Martin-Loeches and
Daniel V. Collins

Med. Sci.2019, 7(5), 66;https://doi.org/10.3390/medsci7050066

22 May 2019

Introduction: diaphragmatic dysfunction is a common cause of slow weaning in mechanically ventilated patients. Diaphragmatic dysfunction in ventilated patients can be global or regional. The aim of our study was to evaluate the motion of the entire d...

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Review

37 Citations

5,587 Views

15 Pages

TRP Channels as Lower Urinary Tract Sensory Targets

Karl-Erik Andersson

Med. Sci.2019, 7(5), 67;https://doi.org/10.3390/medsci7050067

22 May 2019

Several members of the transient receptor potential (TRP) superfamily, including TRPV1, TRPV2, TRPV4, TRM4, TRPM8 and TRPA1, are expressed in the lower urinary tract (LUT), not only in neuronal fibers innervating the bladder and urethra, but also in...

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Med. Sci. - ISSN 2076-3271

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