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Medical Sciences, Volume 2, Issue 1

2014 March - 4 articles

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Articles (4)

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Article

3 Citations

13,764 Views

19 Pages

Characterization of Free and Porous Silicon-Encapsulated Superparamagnetic Iron Oxide Nanoparticles as Platforms for the Development of Theranostic Vaccines

Charles M. Lundquist,
Christopher Loo,
Ismail M. Meraz,
Jorge De La Cerda,
Xuewu Liu and
Rita E. Serda

Med. Sci.2014, 2(1), 51-69;https://doi.org/10.3390/medsci2010051

20 February 2014

Tracking vaccine components from the site of injection to their destination in lymphatic tissue, and simultaneously monitoring immune effects, sheds light on the influence of vaccine components on particle and immune cell trafficking and therapeutic...

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Article

18 Citations

8,966 Views

14 Pages

Cigarette Smoke Alters the Hematopoietic Stem Cell Niche

Robert W. Siggins,
Fokhrul Hossain,
Tayyab Rehman,
John N. Melvan,
Ping Zhang and
David A. Welsh

Med. Sci.2014, 2(1), 37-50;https://doi.org/10.3390/medsci2010037

18 February 2014

Effects of tobacco smoke on hematologic derangements have received little attention. This study employed a mouse model of cigarette smoke exposure to explore the effects on bone marrow niche function. While lung cancer is the most widely studied cons...

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Review

3 Citations

7,661 Views

14 Pages

Foreign or Domestic CARs: Receptor Ligands as Antigen-Binding Domains

Donald R. Shaffer,
Penghui Zhou and
Stephen Gottschalk

Med. Sci.2014, 2(1), 23-36;https://doi.org/10.3390/medsci2010023

28 January 2014

Chimeric antigen receptors (CARs) are increasingly being used in clinical trials to treat a variety of malignant conditions and recent results with CD19-specific CARs showing complete tumor regressions has sparked the interest of researchers and the...

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Review

11,924 Views

22 Pages

Antitumor Immunity and Dietary Compounds

Annalise R. Smith and
Samita Andreansky

Med. Sci.2014, 2(1), 1-22;https://doi.org/10.3390/medsci2010001

27 December 2013

The mechanisms by which natural dietary compounds exert their antitumor effects have been the focus of a large number of research efforts in recent years. Induction of apoptosis by inhibition of cell proliferative pathways is one of the common means...

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