SARS-CoV-2 Infects Hamster Testes
Abstract
:1. Introduction
2. Materials and Methods
2.1. Cells and Viruses Used
2.2. Animal Infection
2.3. Plaque Assays
2.4. Ex Vivo Testes Infection
2.5. Sertoli and Vero Cells Growth Curves
2.6. RT-qPCR
2.7. Histology
2.8. Immunofluorescence Assay
2.9. Quantification and Statistical Analyses
3. Results and Discussion
3.1. Golden Syrian Hamsters Infected with SARS-CoV-2 Show Signs of Mild Disease
3.2. SARS-CoV-2 RNA Was Detected in Testes Tissue without Histopathological Changes
3.3. SARS-CoV-2 Can Infect Cells of the Testicular Tissue Ex Vivo
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Campos, R.K.; Camargos, V.N.; Azar, S.R.; Haines, C.A.; Eyzaguirre, E.J.; Rossi, S.L. SARS-CoV-2 Infects Hamster Testes. Microorganisms 2021, 9, 1318. https://doi.org/10.3390/microorganisms9061318
Campos RK, Camargos VN, Azar SR, Haines CA, Eyzaguirre EJ, Rossi SL. SARS-CoV-2 Infects Hamster Testes. Microorganisms. 2021; 9(6):1318. https://doi.org/10.3390/microorganisms9061318
Chicago/Turabian StyleCampos, Rafael K., Vidyleison N. Camargos, Sasha R. Azar, Clint A. Haines, Eduardo J. Eyzaguirre, and Shannan L. Rossi. 2021. "SARS-CoV-2 Infects Hamster Testes" Microorganisms 9, no. 6: 1318. https://doi.org/10.3390/microorganisms9061318
APA StyleCampos, R. K., Camargos, V. N., Azar, S. R., Haines, C. A., Eyzaguirre, E. J., & Rossi, S. L. (2021). SARS-CoV-2 Infects Hamster Testes. Microorganisms, 9(6), 1318. https://doi.org/10.3390/microorganisms9061318