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Can Gut Microbiota and Lifestyle Help Us in the Handling of Anorexia Nervosa Patients?

Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, Spain
Author to whom correspondence should be addressed.
Microorganisms 2019, 7(2), 58;
Received: 16 January 2019 / Revised: 8 February 2019 / Accepted: 20 February 2019 / Published: 22 February 2019
(This article belongs to the Special Issue Gut Microbiota Diversity Relates to Lifestyle)
PDF [581 KB, uploaded 22 February 2019]


Gut microbiota is composed of different microorganisms that play an important role in the host. New research shows that bidirectional communications happen between intestinal microbiota and the brain, which is known as the gut–brain axis. This communication is significant and could have a negative or positive effect depending on the state of the gut microbiota. Anorexia nervosa (AN) is a mental illness associated with metabolic, immunologic, biochemical, sensory abnormalities, and extremely low body weight. Different studies have shown a dysbiosis in patients with AN. Due to the gut–brain axis, it was observed that some of the symptoms could be improved in these patients by boosting their gut microbiota. This paper highlights some evidence connecting the role of microbiota in the AN onset and disease progress. Finally, a proposal is done to include the microbiota analysis as part of the recovery protocol used to treat AN patients. When conducting clinical studies of gut microbiota in AN patients, dysbiosis is expected to be found. Then the prescription of a personalized treatment rich in prebiotics and probiotics could be proposed to reverse the dysbiosis. View Full-Text
Keywords: eating disorders; anorexia nervosa; gut microbiota; dysbiosis; gut–brain-axis eating disorders; anorexia nervosa; gut microbiota; dysbiosis; gut–brain-axis

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Mendez-Figueroa, V.; Biscaia, J.M.; Mohedano, R.B.; Blanco-Fernandez, A.; Bailen, M.; Bressa, C.; Larrosa, M.; Gonzalez-Soltero, R. Can Gut Microbiota and Lifestyle Help Us in the Handling of Anorexia Nervosa Patients? Microorganisms 2019, 7, 58.

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