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Article

Geriatric Importance of Histopathological Parameters Evaluated in Thyroidectomy Specimens: A Single Center Retrospective Analysis

by
Nesibe Kahraman Çetin
* and
Sinan Can Taşan
Department of Pathology, Faculty of Medicine, Aydın Adnan Menderes University, 09010 Aydın, Turkey
*
Author to whom correspondence should be addressed.
J. Pers. Med. 2024, 14(1), 95; https://doi.org/10.3390/jpm14010095
Submission received: 10 November 2023 / Revised: 30 December 2023 / Accepted: 9 January 2024 / Published: 15 January 2024

Abstract

Nowadays, the aging human population exerts a notable influence on the treatment of thyroid diseases. The most appropriate approach for the treatment of benign and malignant thyroid diseases in older adults has not yet been determined. The aim of our study is to evaluate the effect of thyroidectomies in geriatric patients considering age, sex and histopathological parameters and to determine the importance of thyroidectomy as a treatment option in the geriatric population. A total of 910 cases from all age groups were included, for which thyroidectomies were examined and reported. In accordance with the College of American Pathologists Cancer Protocol for thyroid reporting, considering geriatric patients, the rate of Thyroid Follicular Nodular Disease was significantly higher among the tumor types in the benign tumor group (p = 0.033), while Anaplastic Thyroid Carcinoma rate was higher in the malignant tumor group. The diagnosis rate of malignant tumors was higher in males, reflecting a more advanced pT stage (p < 0.001), larger tumor size (p < 0.001) and increased lymph node involvement rate (p = 0.039). Given that increasing age is associated with a heightened incidence of thyroid disease, the safety of surgery for geriatric patients is an important issue. Thyroidectomy should be considered in the treatment of these patients, especially in males, as the rate of malignant diagnosis and worse histopathological parameters are seen with increasing age.
Keywords: thyroidectomy; malignancy; geriatrics; histopathology; age; sex thyroidectomy; malignancy; geriatrics; histopathology; age; sex

Share and Cite

MDPI and ACS Style

Kahraman Çetin, N.; Taşan, S.C. Geriatric Importance of Histopathological Parameters Evaluated in Thyroidectomy Specimens: A Single Center Retrospective Analysis. J. Pers. Med. 2024, 14, 95. https://doi.org/10.3390/jpm14010095

AMA Style

Kahraman Çetin N, Taşan SC. Geriatric Importance of Histopathological Parameters Evaluated in Thyroidectomy Specimens: A Single Center Retrospective Analysis. Journal of Personalized Medicine. 2024; 14(1):95. https://doi.org/10.3390/jpm14010095

Chicago/Turabian Style

Kahraman Çetin, Nesibe, and Sinan Can Taşan. 2024. "Geriatric Importance of Histopathological Parameters Evaluated in Thyroidectomy Specimens: A Single Center Retrospective Analysis" Journal of Personalized Medicine 14, no. 1: 95. https://doi.org/10.3390/jpm14010095

APA Style

Kahraman Çetin, N., & Taşan, S. C. (2024). Geriatric Importance of Histopathological Parameters Evaluated in Thyroidectomy Specimens: A Single Center Retrospective Analysis. Journal of Personalized Medicine, 14(1), 95. https://doi.org/10.3390/jpm14010095

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