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Open AccessCase Report

Contrast Media Induced Kounis Syndrome: A Case Report

Department of Emergency Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei 231, Taiwan
Department of Emergency Medicine, School of Medicine, Tzu Chi University, Hualien 970, Taiwan
Department of Medical Research, Buddhist Tzu Chi General Hospital, Hualien 970, Taiwan
Author to whom correspondence should be addressed.
Diagnostics 2019, 9(4), 154;
Received: 16 September 2019 / Revised: 7 October 2019 / Accepted: 16 October 2019 / Published: 18 October 2019
(This article belongs to the Special Issue Atherosclerosis and Vascular Imaging)
Kounis syndrome is a rare anaphylactic reaction leading to coronary spasm, acute plaque rupture, or intrastent stenosis. Many types of medicine or environmental factors can potentially trigger Kounis syndrome by mast cell allergic reactions. In severe Kounis syndrome, reduced blood pressure or cardiac arrest may be accompanying symptoms. The treatment strategy for Kounis syndrome is usually difficult due to both cardiac dysfunction and allergic reactions. The delay to intervention to break the vicious circle may cause catastrophic complications. Therefore, early diagnosis is critical for physicians to outline detailed etiology for prevention and treat the cardiac and allergic symptoms in a timely manner. Here, we describe a case presenting rare severe Kounis syndrome with cardiac arrest which occurred after the administration of a contrast media. View Full-Text
Keywords: contrast media; Kounis syndrome; cardiac arrest; acute coronary syndrome contrast media; Kounis syndrome; cardiac arrest; acute coronary syndrome
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Chien, D.-S.; Tsai, A. .-Y.; Lin, P.-C.; Yiang, G.-T.; Wu, M.-Y. Contrast Media Induced Kounis Syndrome: A Case Report. Diagnostics 2019, 9, 154.

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