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Open AccessCase Report

Spontaneous Splenic Rupture as a Rare Initial Presentation in an Acute Lymphoblastic Leukemia Patient

1
Department of Emergency Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei 231, Taiwan
2
Department of Emergency Medicine, School of Medicine, Tzu Chi University, Hualien 970, Taiwan
3
Division of Hematology and Oncology, Department of Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taipei 231, Taiwan
4
Department of Medicine, School of Medicine, Tzu Chi University, Hualien 970, Taiwan
5
Department of Medical Imaging, Taipei Tzu Chi Hospital, the Buddhist Tzu Chi Medical Foundation, New Taipei 231 Taiwan
6
Department of Medical Imaging, School of Medicine, Tzu Chi University, Hualien 970, Taiwan
7
Institute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan
8
Chinese Medicine Department, Show Chwan Memorial Hospital, Changhua 500, Taiwan
*
Authors to whom correspondence should be addressed.
Diagnostics 2019, 9(4), 152; https://doi.org/10.3390/diagnostics9040152
Received: 20 September 2019 / Revised: 15 October 2019 / Accepted: 15 October 2019 / Published: 18 October 2019
(This article belongs to the Special Issue Atherosclerosis and Vascular Imaging)
A spontaneous rupture of the spleen is a rare but critical diagnosis of an acute abdomen, which may accompany unspecific symptoms mimicking acute pancreatitis, rupture of aortic aneurism, or acute coronary syndrome, delaying diagnosis and treatment. In patients that have experienced a severe spleen rupture, hypovolemic shock may cause catastrophic clinical outcomes. Therefore, early diagnosis is very important in order for physicians to declare the etiology for prevention and timely correction of the shock status. Several causes of spontaneous splenic rupture have been reported, including infection, vasculitis, pancreatitis, or hematological malignancies. Acute lymphoblastic leukemia (ALL) remains a rare but important cause of non-traumatic splenic rupture that physicians are required to assess for. Here, we describe a case presenting an acute abdomen due to spontaneous spleen rupture as the first manifestation. The purpose of this case report was to highlight the importance of considering spontaneous ruptures of the spleen as a rare but critical differential diagnosis of an acute abdomen, especially in patients with acute lymphoblastic leukemia. View Full-Text
Keywords: splenic rupture; acute lymphoblastic leukemia; acute abdomen; computed tomography splenic rupture; acute lymphoblastic leukemia; acute abdomen; computed tomography
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MDPI and ACS Style

Wu, M.-Y.; Kao, W.-Y.; Chan, C.-Y.; Yiang, G.-T.; Liao, W.-T.; Chen, C.-S. Spontaneous Splenic Rupture as a Rare Initial Presentation in an Acute Lymphoblastic Leukemia Patient. Diagnostics 2019, 9, 152.

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