Next Article in Journal
Osteoimmunologic and Immune-Aging Signatures in Postmenopausal Women with Periodontitis and Low Bone Mineral Density: A Cross-Sectional Study
Next Article in Special Issue
Assessment of Optimal Stent Implantation with the Use of Optical Coherence Tomography in Patients with Coronary Artery Disease
Previous Article in Journal
SBMN: Similarity-Based Memory Network for the Diagnosis of Vertical Root Fracture in Dental Imaging
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Diagnostics
Volume 16
Issue 5
10.3390/diagnostics16050707
diagnostics-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Review

Multimodality Imaging Approach in the Diagnosis of Constrictive Pericarditis

by
Lucia La Mura
1,*,
Francesca Musella
2,3,
Marianna D’Amato
4,
Maria Lembo
1,
Costantino Mancusi
1,
Marco Ferrone
5,
Ilaria Fucile
1,
Ciro Santoro
6,
Raffaele Izzo
1 and
Giovanni Esposito
1
1
Department of Advanced Biomedical Sciences, “Federico II” University of Naples, 80131 Naples, Italy
2
Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, 118 83 Stockholm, Sweden
3
Cardiology Department, Santa Maria delle Grazie Hospital, 80078 Pozzuoli, Italy
4
Servicio de Cardiologia, Hospital Central de la Defensa Gomez Ulla, 28047 Madrid, Spain
5
Catheterization Laboratory, Division of Cardiology, Montevergine Clinic, 83013 Mercogliano, Italy
6
Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende (CS), 87036 Arcavacata, Italy
*
Author to whom correspondence should be addressed.
Diagnostics 2026, 16(5), 707; https://doi.org/10.3390/diagnostics16050707
Submission received: 26 January 2026 / Revised: 22 February 2026 / Accepted: 25 February 2026 / Published: 27 February 2026
(This article belongs to the Special Issue Multimodal Cardiac Imaging: Diagnostic and Prognostic Advances)
Browse Figures
Review Reports Versions Notes

Abstract

Constrictive pericarditis (CP) results from persistent or insufficiently controlled pericardial inflammation arising from diverse etiologies. It remains a challenging clinical condition, typically presenting with non-specific symptoms that demand a high degree of clinical suspicion and meticulous imaging assessment. As CP progressively impairs both left- and right-sided cardiac function, it can lead to overt heart failure and a marked decline in quality of life, making early recognition crucial. Multimodality imaging plays an essential role in the diagnostic and prognostic evaluation of CP, enabling distinction from restrictive cardiomyopathy (RCM), detection of active pericardial inflammation, and guidance of therapeutic decision-making. Echocardiography provides key hemodynamic insights, including ventricular interdependence and respiratory variation in flow patterns. Cardiac Computed Tomography (CT) offers high-resolution delineation of pericardial thickening and calcification, while Cardiac magnetic resonance (CMR) allows comprehensive characterization of pericardial anatomy, myocardial–pericardial coupling, and inflammatory burden through late gadolinium enhancement (LGE) and parametric mapping. Additionally, positron emission tomography (PET) imaging can identify metabolically active inflammation, aiding in determining the suitability of medical therapy versus pericardiectomy. By integrating these complementary modalities, clinicians can achieve greater diagnostic precision, refine risk stratification, and tailor management strategies, ultimately improving outcomes for patients with constrictive pericarditis.
Keywords: multimodality imaging; constrictive pericarditis; cardiac magnetic resonance; cardiac CT; CMR; PET imaging; nuclear imaging; echocardiography; cardiac inflammatory diseases multimodality imaging; constrictive pericarditis; cardiac magnetic resonance; cardiac CT; CMR; PET imaging; nuclear imaging; echocardiography; cardiac inflammatory diseases
Graphical Abstract

Share and Cite

MDPI and ACS Style

La Mura, L.; Musella, F.; D’Amato, M.; Lembo, M.; Mancusi, C.; Ferrone, M.; Fucile, I.; Santoro, C.; Izzo, R.; Esposito, G. Multimodality Imaging Approach in the Diagnosis of Constrictive Pericarditis. Diagnostics 2026, 16, 707. https://doi.org/10.3390/diagnostics16050707

AMA Style

La Mura L, Musella F, D’Amato M, Lembo M, Mancusi C, Ferrone M, Fucile I, Santoro C, Izzo R, Esposito G. Multimodality Imaging Approach in the Diagnosis of Constrictive Pericarditis. Diagnostics. 2026; 16(5):707. https://doi.org/10.3390/diagnostics16050707

Chicago/Turabian Style

La Mura, Lucia, Francesca Musella, Marianna D’Amato, Maria Lembo, Costantino Mancusi, Marco Ferrone, Ilaria Fucile, Ciro Santoro, Raffaele Izzo, and Giovanni Esposito. 2026. "Multimodality Imaging Approach in the Diagnosis of Constrictive Pericarditis" Diagnostics 16, no. 5: 707. https://doi.org/10.3390/diagnostics16050707

APA Style

La Mura, L., Musella, F., D’Amato, M., Lembo, M., Mancusi, C., Ferrone, M., Fucile, I., Santoro, C., Izzo, R., & Esposito, G. (2026). Multimodality Imaging Approach in the Diagnosis of Constrictive Pericarditis. Diagnostics, 16(5), 707. https://doi.org/10.3390/diagnostics16050707

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop