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Interesting Images
Peer-Review Record

Cell Proliferation PET Imaging with 4DST PET/CT in Colorectal Adenocarcinoma and Adenoma

Diagnostics 2021, 11(9), 1658; https://doi.org/10.3390/diagnostics11091658
by Ryogo Minamimoto 1,* and Hisako Endo 2
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Diagnostics 2021, 11(9), 1658; https://doi.org/10.3390/diagnostics11091658
Submission received: 25 July 2021 / Revised: 6 September 2021 / Accepted: 8 September 2021 / Published: 10 September 2021
(This article belongs to the Collection Interesting Images)

Round 1

Reviewer 1 Report

Manuscript entitled "Cell proliferation PET imaging with 4DST PET/CT in colorectal adenocarcinoma and adenoma"

This work is potentially interesting while some modifications should be made before final acceptance:

  1. The quality of pathological figures should be substantially improved. Some are dark and blur.
  2. Is there any follow up image before surgical treatment?

Author Response

We greatly appreciate your review of our manuscript and the helpful suggestions.

  1. The quality of pathological figures should be substantially improved. Some are dark and blur.

We appreciate the reviewer’s instructive comments. We revised the quality of pathological figures.

      2. Is there any follow up image before surgical treatment?

We appreciate the reviewer’s comments. There were no extra images before surgical treatment.

Reviewer 2 Report

This is a well written case report, describing the 4DST and FDG PET scanning cahracteristics, alongside the histology with special stains, of a patient with a simultaneous adenoma and cancer. While perhaps of moderate impact and interest, it is well written and clear. A larger case series would be of more use in charcterising the findings of these lesions on 4DST PET, and special staining.

Author Response

We greatly appreciate your review of our manuscript.

Round 2

Reviewer 1 Report

The authors do nothing for my suggestion

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