Next Article in Journal
Epithelial-Mesenchymal Transition Proteins in Neuroendocrine Neoplasms: Differential Immunohistochemical Expression in Different Sites and Correlation with Clinico-Pathological Features
Previous Article in Journal
Circulatory Astrocyte and Neuronal EVs as Potential Biomarkers of Neurological Dysfunction in HIV-Infected Subjects and Alcohol/Tobacco Users
Open AccessArticle

Intraoperative Sphenoid Sinus Volume Measurement as an Alternative Technique to Intraoperative Computer Tomography

1
ENT Department with Clinic, Pavlov First Saint Petersburg State Medical University, 197022 St Petersburg, Russia
2
Department of Radiology and Radiation Medicine with X-ray and Radiology Units, Pavlov First Saint Petersburg State Medical University, 197022 St Petersburg, Russia
3
Department of Automation and Control Processes, Saint Petersburg Electrotechnical University “LETI”, 197376 St Petersburg, Russia
4
Radio Engineering Systems Department, Saint Petersburg Electrotechnical University “LETI”, 197376 St Petersburg, Russia
5
Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia
*
Author to whom correspondence should be addressed.
Diagnostics 2020, 10(6), 350; https://doi.org/10.3390/diagnostics10060350
Received: 27 April 2020 / Revised: 24 May 2020 / Accepted: 26 May 2020 / Published: 28 May 2020
(This article belongs to the Section Medical Imaging)
Isolated sphenoid sinus disease (ISSD) is where there is a group of pathologies characterized by inflammation in one or both sphenoid sinuses. Although computer tomography (CT)-based 3D reconstruction remains the gold standard among noninvasive approaches to ISSD diagnostics, no standardized techniques for direct intraoperative measurements of the sphenoid sinus volume in ISSD patients have been documented. We suggest a novel technique for the intraoperative measurement of the sphenoid sinus volume. Our technique is based on filling the sinus with 0.01% methylene blue solution after an endoscopic endonasal sphenoidotomy. The proposed technique was applied to 40 ISSD patients during surgery. Obtained intraoperative measurements were compared to noninvasive measurements from 3D reconstructions based on preoperative CT scans. Our results demonstrated that the obtained measurements did not exhibit significant differences exceeding 0.4 cm3, with CT-scan-based measurements in 39 out of 40 cases (p < 10−6, Wilcoxon sign-rank nonparametric test), thus confirming the accuracy of the proposed technique. Disagreements between direct intraoperative and CT-based measurements in a single case have been attributed to the presence of remaining pathological masses in the sinus, which was further confirmed during the secondary check of the operated sinus. Accordingly, we suggest that the agreement between the CT-based and intraoperative volume measurements can be used as an indicator of the successful elimination of all pathological masses from the sinus without having to perform an adequate exposure of the entire sphenoid sinus to reduce intraoperative bleeding. The proposed technique is accurate and does not require the involvement of specialized intraoperative CT scanners and avoids additional radiation exposure for the patient during an additional postoperation CT scan to confirm the success of the surgery. View Full-Text
Keywords: sphenoid sinus; methylene blue; endoscopy; computer tomography; nasal cavity; neoplasms; paranasal sinuses sphenoid sinus; methylene blue; endoscopy; computer tomography; nasal cavity; neoplasms; paranasal sinuses
Show Figures

Figure 1

MDPI and ACS Style

Karpishchenko, S.; Arustamyan, I.; Stancheva, O.; Sharko, K.; Kaplun, D.; Bogachev, M.I. Intraoperative Sphenoid Sinus Volume Measurement as an Alternative Technique to Intraoperative Computer Tomography. Diagnostics 2020, 10, 350.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop