Abstract
In this paper, we are concerned with a nonlinear system containing some essential symmetrical structures (e.g., cross-diffusion) in the two-dimensional setting, which is proposed to model the biological transport networks. We first provide an a priori blow-up criterion of strong solution of the corresponding Cauchy problem. Based on this, we also establish a priori upper bounds to strong solution for all positive times.
1. Introduction and Main Results
Driven by the need to understand the biological transportation networks (for instance, leaf venation in plants, angiogenesis of blood vessels and neural networks which transport electric charge), biologists and physicists have expressed great interest in investigating the qualitative properties of network structures in the last few decades (see for instance [1,2,3,4,5] and references therein). Recently, Hu and Cai [6] introduced a purely local dynamic adaptation model based on mechanical laws on a graph, which was extended to a continuum one in [7,8,9] that was subsequently studied in the series of papers [10,11,12,13,14,15]. This continuum model, posed in spatial domain Ω, can be read as
The unknown function denotes a scalar pressure of the fluid transported within the network which satisfies Darcy’s type equation due to Darcy’s law for slow flow in the network being valid, and thus represents a driving force for the evolution of the vector-valued conductance that describes the dynamics of networks by using a reaction–diffusion equation consisting of three different mechanisms—pressure effect, diffusion (representing microscopic Brownian process) and an algebraic conductance-relaxation; the given function models the sources and sinks. Values of the parameters (diffusion coefficient), (activation parameter) and (relaxation exponent) are determined by the particular physical applications. For instance, we get from the known experimental studies (see [6,16] and ([8], Section 2) for details) that can be used to describe blood vessel systems in the human body and that corresponds to leaf venation.
From a mathematical perspective, system (1) exhibits two rather peculiar nonlinear structures: in system (1)1 and in (1)2, which may result in yielding several difficulties in the mathematical analysis. For instance, the absence of a priori -bound for may cause the elliptic coefficients in (1)2 to be singular, and thus the solution of (1)2 is too weak to control the nonlinear term in (1)1. These challenges make the cross-diffusion system (1) of interest. We would like to mention that, when system (1) is posed in a bounded domain , it should be supplemented with the initial condition
and the homogeneous Dirichlet boundary conditions
The initial-boundary value problems (1)–(3) has attracted a lot of interest already—see, for instance, ref. [10] for the existence of global weak solution and of local mild solution when that was extended to the case of in [11], ref. [13] for the partial regularity of weak solution, ref. [14] for the regularity of stationary weak solution in two space dimensions and ref. [15] for the existence of local classical large-data solution and of global classical small-data solution.
To our best knowledge, the Cauchy problems (1) and (2) was only studied in [17] when , in which local existence as well as blow-up criterion for large initial data and global existence for small initial data were established based on being a Hilbert space; however, there is no result on the Cauchy problems (1) and (2) on . Our goal is to fill this gap. It is worthwhile pointing out that the important problem of the mathematical theory concerning the Cauchy problems (1) and (2) is whether or not the global in time smooth solution exists for any prescribed smooth initial data. Hence, in the absence of a global well-posedness theory, establishing a priori estimates is of major importance for both theoretical and practical purposes, which motivates us to investigate an a priori blow-up criterion and a priori upper bounds of strong solutions to system (1) and (2) with . We would like remark that, in contrast to system (1) and (2) with , not being a Hilbert space poses obstacles with adopting the same strategies in [17] to study the Cauchy problems (1) and (2) with . To overcome this challenge, we will derive the a priori -bound for to rule out the degeneracy and develop some new dissipation mechanisms hidden in the system (1) and (2) by fully utilizing some essential symmetrical structures of system when .
Before stating our main results, we need to layout some notations. and denote the usual Hilbert space and Lebesgue space with the norms and (or and for short), respectively. The functions in these spaces are usually understood to be real valued. If no confusion is likely, we shall use the same notation for similar spaces of vector-valued functions and of matrix-valued functions, for instance,
Throughout this paper, we will use to denote for some uniform constant . Unless specified, the values of the constants may vary line by line according to the context.
With the aforementioned notations, we now state our first result as follows.
Theorem 1.
Remark 1.
Invoking the blow-up criterion (4) obtained in Theorem 1, we can further present that the local strong solution of the Cauchy problem (1) and (2) can be extended to a global one.
Theorem 2.
Remark 2.
As far as we are concerned, even though there are substantial results regarding the system (1) on or a bounded domain , there are not yet any on . Theorem 1 and Theorem 2 seem to be the first rigorous theoretical analysis on the initial-value problem (1) and (2) on and are a first step toward filling this gap.
Remark 3.
Compared to the initial-value problem (1) and (2) on in [17], establishing an a priori blow-up criterion (4) and a priori upper bounds (5) are nontrivial in the sense that the benefit emanating from being a Hilbert space will be not granted and that our strategy depends on the weight Hardy inequality over (see (12)) as well as seeking some new estimates.
2. Blow-Up Criterion. Proof of Theorem 1
Clearly, by employing a standard bootstrap argument, we can extend this strong solution to the maximal interval of existence , where either or . If , then we have
and vice versa. The goal of this section is to further establish a more precise blow-up criterion for such strong solution, which allows us to extend the local strong solution to a global one in the next section. To this end, for any we abbreviate
for simplicity. We now begin with establishing the following a priori estimates to the strong solution of systems (1) and (2) on .
Lemma 1.
Proof.
Without loss of generality, we may assume that is sufficiently smooth. The general case can be dealt with by taking an approximation procedure.
We proceed along the lines of the proof of ([17], Lemma 3.1) and have
For any , by integrating (9) from 0 to t, we infer that
where the function solves the following Poisson equation
To estimate the terms related to on the right-hand side of (10), by using as a test function in (11), we obtain from the integration by parts that
Recalling the Hardy inequality over ([19])
and employing Hölder’s inequality, we arrive at
From this, we conclude that
This together with (10) yields that
where we used Sobolev’s embedding , Young’s inequality and the fact in the last inequality.
Next, taking the inner product of with and using the integration by parts, we can obtain
Taking the inner product of with p, we can obtain from the integration by parts that
Similarly, we conclude from Hölder’s inequality, Sobolev’s inequality and Hardy’s inequality (12) that
which together with (13) yields that
For any , we integrate the above inequality from 0 to t and thus obtain
This completes the proof of Lemma 1. □
To obtain the higher-order estimates of the solution component , we should establish the higher-order estimates of the solution component p.
Lemma 2.
Proof.
We begin with establishing the estimate (16). Differentiating with respect to for , we have
By taking the inner product of (18) with , we obtain from the integration by parts that
Hence, it reduces to
Invoking Hölder’s inequality and Hardy’s inequality (12), the third term on the right-hand side of (19) can be controlled as follows:
Based on this, we get from Hölder’s inequality and Young’s inequality that
From this, one arrives at
which implies that
Note that, for any , Hölder’s inequality, Sobolev’s embedding, Young’s inequality and Lemma 1 yield that
and similarly that
Hence, we can conclude from (20) that, for any ,
This indicates that (16) holds.
We now turn to the higher-order estimate (17). To achieve this, differentiating (18) with respect to for , we obtain
Then, multiplying (22) by and using the integration by parts, we have
Since
we have
We now use Hölder’s inequality and Hardy’s inequality (12) to estimate the rightmost term of the above equation as follows:
One has
By employing Young’s inequality, we can deduce that
and thus that
We estimate the terms on the right-hand side of (23) one by one. Firstly, we conclude from Hölder’s inequality, Sobolev’s embedding, the interpolation, Young’s inequality and Lemma 1 that
Secondly, we get from a similar procedure that, for any ,
With the improved a priori estimates on p at hand, we can directly derive the higher-order estimates of the solution component under the same assumptions as above.
Lemma 3.
Proof.
Similar to ([17], Lemma 3.3), we get that there exists a positive constant independent of t such that
We estimate the terms on the right-hand side of (24) one by one. For the first term on the right-hand side of (24), we obtain from Hölder’s inequality, the interpolation inequality, Young’s inequality and Lemma 1 that
which together with Lemma 2 yields that
To estimate the second term on the right-hand side of (24), by using the Leibniz’s product rule and Hölder’s inequality, we obtain
For , a straightforward application of the interpolation inequality yields that
and thus that
On the other hand, for , we have from Hölder’s inequality and the interpolation inequality that
for any and thus
This completes the proof of Lemma 3. □
Invoking Lemmas 1–3, we now establish a more precise blow-up criterion for the strong solution as follows.
Lemma 4.
Proof.
We can first deduce from Lemma 3 that, for and all ,
and that for and all ,
Hence, Gronwall’s inequality implies that, for ,
and that, for ,
By employing Lemma 1 again, we conclude that
if and only if
for , and
for , where . This completes the proof of Lemma 4. □
Based on Lemma 4, we now prove Theorem 1.
Proof of Theorem 1.
The blow-up criterion is a by-product of Lemma 4. Thus, we have completed the proof of Theorem 1. □
3. Global Existence. Proof of Theorem 2
In this section, invoking blow-up criterion (4), we show that the local strong solution of the Cauchy problem (1) and (2) is global indeed in the two-dimensional setting.
Lemma 5.
Proof.
We begin with . We now apply the operator () to :
Then, taking the inner product of (29) with and using the integration by parts, we obtain
Due to and , we then get from Hölder’s inequality and (30) that
We use the interpolation inequality and Lemma 1 to show
Hence, by employing (16) with , it arrives at
On the other hand, a direct application of the interpolation inequality yields that for
which leads to
Here, we used the fact that , due to . From this, one then has
Similarly, we also have
Here, we used the fact that due to . Whereupon, invoking the above inequalities, we infer from (31) and Lemma 1 that
Note that and , due to . Thus, Young’s inequality implies from the above inequality that
for two positive constants independent of t. Furthermore, taking
under our assumptions, then one arrives at
Finally, a time integration of the above inequality shows that, for all ,
By means of Lemma 5 and blow-up criterion (4), we can proceed to prove Theorem 2.
Proof of Theorem 2.
By taking in (32), we can get from Lemma 5 that
4. Discussion
In this section, let us begin with presenting a short summary of our main results for the nonlinear PDE system (1) and (2) in the two-dimensional setting:
- Invoking an a priori blow-up criterion and seeking some suitable estimates, we establish a priori upper bounds to a strong solution for all positive times.
We conclude this section by providing two unsolved problems which will be the subject of our future research:
Author Contributions
Conceptualization, J.S. and B.L.; Methodology, J.S. and B.L.; Validation, J.S.; Writing—original draft, B.L.; and Writing—review and editing, J.S.
Funding
This research received no external funding.
Acknowledgments
The authors are very grateful to the anonymous referees for their valuable comments and suggestions, which greatly improved the manuscript, and to editor for his/her kind help.
Conflicts of Interest
The authors declare no conflict of interest.
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