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Glycosylation of Immune Receptors in Cancer

Department of Medicinal Chemistry and Molecular Pharmacology, Purdue Institute of Drug Discovery, Purdue Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA
Author to whom correspondence should be addressed.
Academic Editor: Hamed Jafar-Nejad
Cells 2021, 10(5), 1100;
Received: 2 April 2021 / Revised: 2 May 2021 / Accepted: 3 May 2021 / Published: 4 May 2021
(This article belongs to the Special Issue Glycosylation and Deglycosylation in Animal Development)
Evading host immune surveillance is one of the hallmarks of cancer. Immune checkpoint therapy, which aims to eliminate cancer progression by reprogramming the antitumor immune response, currently occupies a solid position in the rapidly expanding arsenal of cancer therapy. As most immune checkpoints are membrane glycoproteins, mounting attention is drawn to asking how protein glycosylation affects immune function. The answers to this fundamental question will stimulate the rational development of future cancer diagnostics and therapeutic strategies. View Full-Text
Keywords: glycosylation; N-glycan; immune receptor; immune checkpoint therapy; cancer glycosylation; N-glycan; immune receptor; immune checkpoint therapy; cancer
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MDPI and ACS Style

Sun, R.; Kim, A.M.J.; Lim, S.-O. Glycosylation of Immune Receptors in Cancer. Cells 2021, 10, 1100.

AMA Style

Sun R, Kim AMJ, Lim S-O. Glycosylation of Immune Receptors in Cancer. Cells. 2021; 10(5):1100.

Chicago/Turabian Style

Sun, Ruoxuan; Kim, Alyssa M.J.; Lim, Seung-Oe. 2021. "Glycosylation of Immune Receptors in Cancer" Cells 10, no. 5: 1100.

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