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Cancers 2018, 10(2), 30; https://doi.org/10.3390/cancers10020030

Volumetric Modulated Arc (Radio) Therapy in Pets Treatment: The “La Cittadina Fondazione” Experience

1
La Cittadina Fondazione Studi e Ricerche Veterinarie, 26014 Romanengo, Italy
2
Azienda Socio Sanitaria Territoriale della provincia di Lodi, 26841 Casalpusterlengo, Italy
*
Author to whom correspondence should be addressed.
Received: 3 November 2017 / Revised: 29 December 2017 / Accepted: 16 January 2018 / Published: 24 January 2018
(This article belongs to the Special Issue Intensity Modulated Radiation Therapy)
Full-Text   |   PDF [298 KB, uploaded 24 January 2018]

Abstract

Volumetric Modulated Arc Therapy (VMAT) is a modern technique, widely used in human radiotherapy, which allows a high dose to be delivered to tumor volumes and low doses to the surrounding organs at risk (OAR). Veterinary clinics takes advantage of this feature due to the small target volumes and distances between the target and the OAR. Sparing the OAR permits dose escalation, and hypofractionation regimens reduce the number of treatment sessions with a simpler manageability in the veterinary field. Multimodal volumes definition is mandatory for the small volumes involved and a positioning device precisely reproducible with a setup confirmation is needed before each session for avoiding missing the target. Additionally, the elaborate treatment plan must pursue hard constraints and objectives, and its feasibility must be evaluated with a per patient quality control. The aim of this work is to report results with regard to brain meningiomas and gliomas, trigeminal nerve tumors, brachial plexus tumors, adrenal tumors with vascular invasion and rabbit thymomas, in comparison with literature to determine if VMAT is a safe and viable alternative to surgery or chemotherapy alone, or as an adjuvant therapy in pets. View Full-Text
Keywords: VMAT; meningiomas; gliomas; trigeminal nerve tumors; brachial plexus tumors; adrenal tumors; rabbit thymomas VMAT; meningiomas; gliomas; trigeminal nerve tumors; brachial plexus tumors; adrenal tumors; rabbit thymomas
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Dolera, M.; Malfassi, L.; Carrara, N.; Finesso, S.; Marcarini, S.; Mazza, G.; Pavesi, S.; Sala, M.; Urso, G. Volumetric Modulated Arc (Radio) Therapy in Pets Treatment: The “La Cittadina Fondazione” Experience. Cancers 2018, 10, 30.

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