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Functionalized Mesoporous Thin Films for Biotechnology

Institute of Inorganic Chemistry, Graz University of Technology, 8010 Graz, Austria
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Academic Editors: Francesco Gentile and Gobind Das
Micromachines 2021, 12(7), 740; https://doi.org/10.3390/mi12070740
Received: 2 June 2021 / Revised: 17 June 2021 / Accepted: 21 June 2021 / Published: 24 June 2021
(This article belongs to the Special Issue Advances in Biomedical Nanotechnology)
Mesoporous materials bear great potential for biotechnological applications due to their biocompatibility and versatility. Their high surface area and pore interconnection allow the immobilization of molecules and their subsequent controlled delivery. Modifications of the mesoporous material with the addition of different chemical species, make them particularly suitable for the production of bioactive coatings. Functionalized thin films of mesoporous silica and titania can be used as scaffolds with properties as diverse as promotion of cell growth, inhibition of biofilms formation, or development of sensors based on immobilized enzymes. The possibility to pattern them increase their appeal as they can be incorporated into devices and can be tailored both with respect to architecture and functionalization. In fact, selective surface manipulation is the ground for the fabrication of advanced micro devices that combine standard micro/nanofluids with functional materials. In this review, we will present the advantages of the functionalization of silica and titania mesoporous materials deposited in thin film. Different functional groups used to modify their properties will be summarized, as well as functionalization methods and some examples of applications of modified materials, thus giving an overview of the essential role of functionalization to improve the performance of such innovative materials. View Full-Text
Keywords: mesoporous thin films; silica; titania; functionalization; biotechnology; biomedicine mesoporous thin films; silica; titania; functionalization; biotechnology; biomedicine
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MDPI and ACS Style

Sartori, B.; Amenitsch, H.; Marmiroli, B. Functionalized Mesoporous Thin Films for Biotechnology. Micromachines 2021, 12, 740. https://doi.org/10.3390/mi12070740

AMA Style

Sartori B, Amenitsch H, Marmiroli B. Functionalized Mesoporous Thin Films for Biotechnology. Micromachines. 2021; 12(7):740. https://doi.org/10.3390/mi12070740

Chicago/Turabian Style

Sartori, Barbara, Heinz Amenitsch, and Benedetta Marmiroli. 2021. "Functionalized Mesoporous Thin Films for Biotechnology" Micromachines 12, no. 7: 740. https://doi.org/10.3390/mi12070740

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