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Open AccessArticle

Rapid and Sensitive Detection of Bisphenol A Based on Self-Assembly

Key Laboratory of Optoelectronic Technology and Systems of Ministry of Education of China, Chongqing University, Chongqing 400044, China
Author to whom correspondence should be addressed.
Micromachines 2020, 11(1), 41;
Received: 27 November 2019 / Revised: 23 December 2019 / Accepted: 27 December 2019 / Published: 30 December 2019
(This article belongs to the Special Issue Microelectrode Arrays and Application to Medical Devices)
Bisphenol A (BPA) is an endocrine disruptor that may lead to reproductive disorder, heart disease, and diabetes. Infants and young children are likely to be vulnerable to the effects of BPA. At present, the detection methods of BPA are complicated to operate and require expensive instruments. Therefore, it is quite vital to develop a simple, rapid, and highly sensitive method to detect BPA in different samples. In this study, we have designed a rapid and highly sensitive biosensor based on an effective self-assembled monolayer (SAM) and alternating current (AC) electrokinetics capacitive sensing method, which successfully detected BPA at nanomolar levels with only one minute. The developed biosensor demonstrates a detection of BPA ranging from 0.028 μg/mL to 280 μg/mL with a limit of detection (LOD) down to 0.028 μg/mL in the samples. The developed biosensor exhibited great potential as a portable BPA biosensor, and further development of this biosensor may also be useful in the detection of other small biochemical molecules. View Full-Text
Keywords: alternating current (AC) electrokinetics; bisphenol A; self-assembly; biosensor alternating current (AC) electrokinetics; bisphenol A; self-assembly; biosensor
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MDPI and ACS Style

Luo, H.; Lin, X.; Peng, Z.; Song, M.; Jin, L. Rapid and Sensitive Detection of Bisphenol A Based on Self-Assembly. Micromachines 2020, 11, 41.

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