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Microdroplet Synthesis of Silver Nanoparticles with Controlled Sizes

School of Pharmaceutical Sciences, Central South University, Changsha 410013, China
Hunan Key Laboratory Cultivation Base of the Research and Development of Novel Pharmaceutical Preparations, Changsha 410219, China
Author to whom correspondence should be addressed.
Micromachines 2019, 10(4), 274;
Received: 12 March 2019 / Revised: 19 April 2019 / Accepted: 19 April 2019 / Published: 24 April 2019
PDF [2345 KB, uploaded 25 April 2019]


A method was developed to synthesize silver nanoparticles with controlled size and Localized Surface Plasmon Resonance (LSPR) wavelength. In a microchip, droplets with high monodispersity and stability were produced. Using droplets as microreactors, seed-mediated growth approach was successfully applied for silver nanoparticles preparation. It was observed that nanoparticles size and LSPR wavelength could be optimized via adjusting synthesis conditions, such as droplets heating temperature, reaction time, and concentration of silver seeds and silver nitrate in aqueous phase. These results indicated that the proposed microdevices could provide a convenient and inexpensive approach for preparing nanoparticles with optimum properties. View Full-Text
Keywords: silver nanoparticle; microchip; microdroplet silver nanoparticle; microchip; microdroplet

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Hong, T.; Lu, A.; Liu, W.; Chen, C. Microdroplet Synthesis of Silver Nanoparticles with Controlled Sizes. Micromachines 2019, 10, 274.

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