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Chitosans for Tissue Repair and Organ Three-Dimensional (3D) Bioprinting
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Advanced Polymers for Three-Dimensional (3D) Organ Bioprinting

by Xiaohong Wang 1,2
Center of 3D Printing & Organ Manufacturing, School of Fundamental Sciences, China Medical University (CMU), No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China
Center of Organ Manufacturing, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China
Micromachines 2019, 10(12), 814;
Received: 25 October 2019 / Revised: 17 November 2019 / Accepted: 19 November 2019 / Published: 25 November 2019
(This article belongs to the Special Issue 3D Printing for Tissue Engineering and Regenerative Medicine)
Three-dimensional (3D) organ bioprinting is an attractive scientific area with huge commercial profit, which could solve all the serious bottleneck problems for allograft transplantation, high-throughput drug screening, and pathological analysis. Integrating multiple heterogeneous adult cell types and/or stem cells along with other biomaterials (e.g., polymers, bioactive agents, or biomolecules) to make 3D constructs functional is one of the core issues for 3D bioprinting of bioartificial organs. Both natural and synthetic polymers play essential and ubiquitous roles for hierarchical vascular and neural network formation in 3D printed constructs based on their specific physical, chemical, biological, and physiological properties. In this article, several advanced polymers with excellent biocompatibility, biodegradability, 3D printability, and structural stability are reviewed. The challenges and perspectives of polymers for rapid manufacturing of complex organs, such as the liver, heart, kidney, lung, breast, and brain, are outlined.
Keywords: three-dimensional (3D) printing; organ manufacturing; biomaterials; polymers; stem cells three-dimensional (3D) printing; organ manufacturing; biomaterials; polymers; stem cells
MDPI and ACS Style

Wang, X. Advanced Polymers for Three-Dimensional (3D) Organ Bioprinting. Micromachines 2019, 10, 814.

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