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Open AccessReview

Regulation of cry Gene Expression in Bacillus thuringiensis

by 1,2, 1, 1,* and 2,3,*
1
State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China
2
INRA, UMR1319 Micalis, La Minière, Guyancourt 78280, France
3
AgroParisTech, UMR Micalis, Jouy-en-Josas 78352 cedex, France
*
Authors to whom correspondence should be addressed.
Toxins 2014, 6(7), 2194-2209; https://doi.org/10.3390/toxins6072194
Received: 3 June 2014 / Revised: 11 July 2014 / Accepted: 15 July 2014 / Published: 23 July 2014
(This article belongs to the Special Issue Bacillus thuringiensis Toxins)
Bacillus thuringiensis differs from the closely related Bacillus cereus group species by its ability to produce crystalline inclusions. The production of these crystals mainly results from the expression of the cry genes, from the stability of their transcripts and from the synthesis, accumulation and crystallization of large amounts of insecticidal Cry proteins. This process normally coincides with sporulation and is regulated by various factors operating at the transcriptional, post-transcriptional, metabolic and post-translational levels. View Full-Text
Keywords: cry gene; transcription; metabolism; crystallization; protein expression; regulation; RNA stability cry gene; transcription; metabolism; crystallization; protein expression; regulation; RNA stability
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Deng, C.; Peng, Q.; Song, F.; Lereclus, D. Regulation of cry Gene Expression in Bacillus thuringiensis. Toxins 2014, 6, 2194-2209.

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