Exposure Assessment and Risk Characterization of Aflatoxin M1 Intake through Consumption of Milk and Yoghurt by Student Population in Serbia and Greece

Udovicki, Bozidar; Djekic, Ilija; Kalogianni, Eleni P.; Rajkovic, Andreja

doi:10.3390/toxins11040205

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Exposure Assessment and Risk Characterization of Aflatoxin M1 Intake through Consumption of Milk and Yoghurt by Student Population in Serbia and Greece

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Department of Food Safety and Quality Management, Faculty of Agriculture, University of Belgrade, 11080 Zemun-Belgrade, Serbia

Department of Food Technology, Alexander Technological Educational Institute of Thessaloniki, 57400 Thessaloniki, Greece

Department of Food Technology, Food Safety and Health, Faculty of Bioscience Engineering, Ghent University, B-9000 Ghent, Belgium

Author to whom correspondence should be addressed.

Toxins 2019, 11(4), 205; https://doi.org/10.3390/toxins11040205

Received: 25 February 2019 / Revised: 28 March 2019 / Accepted: 2 April 2019 / Published: 5 April 2019

(This article belongs to the Special Issue Fungal Infestations in Humans, Animals, Crops)

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Abstract

The objective of this research was to perform an exposure assessment of aflatoxin M1 (AFM1) intake through the consumption of milk and yoghurt by the student population in Serbia and Greece. A food consumption survey of milk and yoghurt was performed during the first half of 2018 in the two countries with at least 500 interviewees (aged between 18 and 27 years) per country, covering their dietary habits and body weight based on one-day and seven-day recall methods. Values for the concentration of AFM1 were extracted from published research. Finally, a Monte Carlo analysis of 100,000 iterations was performed to estimate the intake of AFM1 from the consumption of the two dairy products. Results revealed that the estimated average exposure of students to AFM1 was in the range of 1.238–2.674 ng kg⁻¹ bw day⁻¹ for Serbia, and 0.350–0.499 ng kg⁻¹ bw day⁻¹ for Greece, depending on the dietary recall method employed. High estimations for hepatocellular carcinoma (HCC) cases/year/10⁵ individuals, depending on the prevalence of Hepatitis B virus surface antigen positive individuals (HBsAg+), were 0.0036–0.0047 and 0.0007–0.0009 for Serbia and Greece, respectively. Presented Margin of Exposure (MOE) and Hazard Index (HI) values indicate increased risk from exposure to AFM1, particularly in Serbia. View Full-Text

Keywords: milk; aflatoxin M1; exposure assessment; risk characterization; Monte Carlo; HCC; MOE

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MDPI and ACS Style

Udovicki, B.; Djekic, I.; Kalogianni, E.P.; Rajkovic, A. Exposure Assessment and Risk Characterization of Aflatoxin M1 Intake through Consumption of Milk and Yoghurt by Student Population in Serbia and Greece. Toxins 2019, 11, 205. https://doi.org/10.3390/toxins11040205

AMA Style

Udovicki B, Djekic I, Kalogianni EP, Rajkovic A. Exposure Assessment and Risk Characterization of Aflatoxin M1 Intake through Consumption of Milk and Yoghurt by Student Population in Serbia and Greece. Toxins. 2019; 11(4):205. https://doi.org/10.3390/toxins11040205

Chicago/Turabian Style

Udovicki, Bozidar, Ilija Djekic, Eleni P. Kalogianni, and Andreja Rajkovic. 2019. "Exposure Assessment and Risk Characterization of Aflatoxin M1 Intake through Consumption of Milk and Yoghurt by Student Population in Serbia and Greece" Toxins 11, no. 4: 205. https://doi.org/10.3390/toxins11040205

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Exposure Assessment and Risk Characterization of Aflatoxin M1 Intake through Consumption of Milk and Yoghurt by Student Population in Serbia and Greece

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