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Toxins 2018, 10(9), 345; https://doi.org/10.3390/toxins10090345

Effects of Nano-Composite Adsorbents on the Growth Performance, Serum Biochemistry, and Organ Weights of Broilers Fed with Aflatoxin-Contaminated Feed

1
Institute of Tropical Agriculture and Food Security, Universiti Putra Malaysia, Serdang 43400, Malaysia
2
Faculty of Food Science and Technology, Universiti Putra Malaysia, Serdang 43400, Malaysia
3
Department of Animal Science, Faculty of Agriculture, Universiti Putra Malaysia, Serdang 43400, Malaysia
*
Author to whom correspondence should be addressed.
Received: 21 June 2018 / Revised: 28 June 2018 / Accepted: 3 July 2018 / Published: 27 August 2018
(This article belongs to the Collection Understanding Mycotoxin Occurrence in Food and Feed Chains)
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Abstract

The exploration of feed mycotoxin adsorbents to mitigate the adverse effects of mycotoxins on animals has received increasing attention over the last decade. The present study was conducted to assess the efficacy of nano-composite magnetic graphene oxide with chitosan (MGO-CTS) adsorbents against feed contaminated with ~20 ng/g (ppb) aflatoxin (AF). A total of three hundred 1-day-old chicks were randomly distributed into six dietary treatment groups, as follows: basal diet (broilers fed a diet with neither AF nor MGO-CTS added, T1), basal diet + 0.25% MGO-CTS (T2), basal diet + 0.50% MGO-CTS (T3), AF diet + 0.25% MGO-CTS (T4), AF diet + 0.50% MGO-CTS (T5), and AF diet (T6). The two inclusion levels (0.25 and 0.50%) of MGO-CTS significantly (p < 0.05) improved the growth performances and feed conversion ratios of the AF-treated chicks at 1–35 days of age, and the impact was more pronounced for 0.5% MGO-CTS. The AF intake markedly increased the relative weights of the liver and kidney, resulting in significant alterations in the serum biochemical parameters, such as albumins, alkaline phosphatase, and SGPT/alanine (ALT), at 35 days of age. However, the chickens fed 0.5% MGO-CTS with AF diets had apparent recovery or restoration of AF-induced organ lesions and aberrant serum profiles. A significant (p < 0.05) reduction in the total AFs was observed in the gastrointestinal tracts of the chickens fed 0.25% or 0.50% adsorbent in combination with AF feed (T4 and T5), with decreases of 28.9% and 53.5%, respectively, compared with that in the chickens fed an AF-contaminated diet (T6). The results of the study indicated that a higher concentration of MGO-CTS (0.50%) was effective in improving the overall performance of broiler chickens by preventing the adverse effects associated with aflatoxicosis. View Full-Text
Keywords: aflatoxicosis; broiler performance; blood profiles; organ weights; nano-composite adsorbent aflatoxicosis; broiler performance; blood profiles; organ weights; nano-composite adsorbent
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Saminathan, M.; Selamat, J.; Abbasi Pirouz, A.; Abdullah, N.; Zulkifli, I. Effects of Nano-Composite Adsorbents on the Growth Performance, Serum Biochemistry, and Organ Weights of Broilers Fed with Aflatoxin-Contaminated Feed. Toxins 2018, 10, 345.

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