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Volume 17
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10.3390/nu17050888
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Review

Impacts of Yacon Syrup (Smallanthus sonchifolius) on Human Health: A Systematic Review of Scientific Evidence from the Last Decade

by
Marcos F. Pereira
1,
Igor de Codes Soares
1,
Marília Magalhães Cabral
2,
Paula A. de Freitas
2,
Gabriel M. A. Sousa
1,
Saulo Chaves Magalhães
1,
Antônio Augusto Ferreira Carioca
3,
Maria Rayane C. de Oliveira
2,
Francisco Ernani A. Magalhães
2,
Ariclecio C. de Oliveira
1,2,
Renalison Farias-Pereira
4 and
Keciany Alves de Oliveira
1,2,*
1
Higher Institute of Biomedical Sciences, State University of Ceara-UECE, Fortaleza 60714-903, CE, Brazil
2
Postgraduate Program in Nutrition and Health, State University of Ceara-UECE, Fortaleza 60714-903, CE, Brazil
3
Department of Nutrition, Postgraduate Studies in Public Health, University of Fortaleza, Fortaleza 60811-905, CE, Brazil
4
Department of Biological Sciences, The Dorothy and George Hennings College of Science, Mathematics and Technology, Kean University, Union, NJ 07083, USA
*
Author to whom correspondence should be addressed.
Nutrients 2025, 17(5), 888; https://doi.org/10.3390/nu17050888
Submission received: 7 February 2025 / Revised: 27 February 2025 / Accepted: 27 February 2025 / Published: 1 March 2025
(This article belongs to the Special Issue Association Between Lipid Metabolism and Obesity)
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Abstract

Background/Objectives: Yacon syrup (Smallanthus sonchifolius) has gained attention due to its high concentration of fructooligosaccharides (FOSs) and associated health benefits. This systematic review aimed to evaluate the effects of yacon syrup on metabolic parameters and intestinal health in humans over the last decade. Methods: Following PRISMA guidelines, we conducted a systematic search in databases, including Medline (PubMed), Science Direct, Embase, Scopus, and SciELO, up to October 2024. Inclusion criteria focused on clinical trials examining the impact of yacon syrup on glycemic control, lipid profile, insulin sensitivity, appetite regulation, and gut microbiota in healthy, overweight, or obese individuals. Seven studies met the inclusion criteria, encompassing 161 participants from diverse populations. Results: Yacon syrup supplementation demonstrated significant reductions in fasting insulin, HOMA-IR, and LDL cholesterol, alongside improvements in satiety and intestinal transit time. Acute supplementation with yacon syrup had inconsistent results for postprandial glycemia and insulin levels, probably due to prior individual gut microbiota composition. Longer interventions with yacon syrup were associated with enhanced microbiota modulation and appetite regulation, particularly in women. Mild gastrointestinal discomfort was reported, but with the continued use of yacon syrup, the symptoms decreased. Yacon syrup presents promising health benefits, including improved insulin sensitivity, weight management, and gut health. However, further research is needed to establish optimal dosing and long-term safety. Conclusions: This review highlights the potential of yacon syrup as a functional supplement for metabolic and gastrointestinal health.
Keywords: yacon syrup; fructooligosaccharides; metabolic health; gut microbiota; systematic review; insulin sensitivity; satiety; dietary supplements yacon syrup; fructooligosaccharides; metabolic health; gut microbiota; systematic review; insulin sensitivity; satiety; dietary supplements

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MDPI and ACS Style

Pereira, M.F.; Soares, I.d.C.; Cabral, M.M.; de Freitas, P.A.; Sousa, G.M.A.; Magalhães, S.C.; Carioca, A.A.F.; de Oliveira, M.R.C.; Magalhães, F.E.A.; de Oliveira, A.C.; et al. Impacts of Yacon Syrup (Smallanthus sonchifolius) on Human Health: A Systematic Review of Scientific Evidence from the Last Decade. Nutrients 2025, 17, 888. https://doi.org/10.3390/nu17050888

AMA Style

Pereira MF, Soares IdC, Cabral MM, de Freitas PA, Sousa GMA, Magalhães SC, Carioca AAF, de Oliveira MRC, Magalhães FEA, de Oliveira AC, et al. Impacts of Yacon Syrup (Smallanthus sonchifolius) on Human Health: A Systematic Review of Scientific Evidence from the Last Decade. Nutrients. 2025; 17(5):888. https://doi.org/10.3390/nu17050888

Chicago/Turabian Style

Pereira, Marcos F., Igor de Codes Soares, Marília Magalhães Cabral, Paula A. de Freitas, Gabriel M. A. Sousa, Saulo Chaves Magalhães, Antônio Augusto Ferreira Carioca, Maria Rayane C. de Oliveira, Francisco Ernani A. Magalhães, Ariclecio C. de Oliveira, and et al. 2025. "Impacts of Yacon Syrup (Smallanthus sonchifolius) on Human Health: A Systematic Review of Scientific Evidence from the Last Decade" Nutrients 17, no. 5: 888. https://doi.org/10.3390/nu17050888

APA Style

Pereira, M. F., Soares, I. d. C., Cabral, M. M., de Freitas, P. A., Sousa, G. M. A., Magalhães, S. C., Carioca, A. A. F., de Oliveira, M. R. C., Magalhães, F. E. A., de Oliveira, A. C., Farias-Pereira, R., & de Oliveira, K. A. (2025). Impacts of Yacon Syrup (Smallanthus sonchifolius) on Human Health: A Systematic Review of Scientific Evidence from the Last Decade. Nutrients, 17(5), 888. https://doi.org/10.3390/nu17050888

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