Next Article in Journal
Aging-Related Behavioral, Adiposity, and Glucose Impairments and Their Association following Prenatal Alcohol Exposure in the C57BL/6J Mouse
Next Article in Special Issue
Anti-Inflammatory and Antioxidant Effects of Carvacrol on N-Methyl-N′-Nitro-N-Nitrosoguanidine (MNNG) Induced Gastric Carcinogenesis in Wistar Rats
Previous Article in Journal
Determinants of Suboptimal Gestational Weight Gain among Antenatal Women Residing in the Highest Gross Domestic Product (GDP) Region of Malaysia
Previous Article in Special Issue
Investigation of the Effect of Curcumin on Protein Targets in NAFLD Using Bioinformatic Analysis
 
 
Review

Targeting Cardiovascular Diseases by Flavonols: An Update

1
Department of Social Medicine and Public Health, Medical University of Warsaw, Oczki Str. 3, 02-007 Warsaw, Poland
2
Department of Clinical Dietetics, Faculty of Health Sciences, Medical University of Warsaw, E Ciołka Str. 27, 01-445 Warsaw, Poland
*
Author to whom correspondence should be addressed.
Academic Editor: Přemysl Mladěnka
Nutrients 2022, 14(7), 1439; https://doi.org/10.3390/nu14071439
Received: 23 February 2022 / Revised: 24 March 2022 / Accepted: 28 March 2022 / Published: 30 March 2022
Flavonols are one of the most plentiful flavonoid subclasses found in natural products and are extensively used as dietary supplements. Numerous in vitro and in vivo studies have shown the cardioprotective properties of flavonols, especially quercetin. This group of substances exerts positive impacts primarily due to their antiatherogenic, antithrombotic, and antioxidant activities. The potential of flavonols to promote vasodilation and regulation of apoptotic processes in the endothelium are other beneficial effects on the cardiovascular system. Despite promising experimental findings, randomized controlled trials and meta-analyses have yielded inconsistent results on the influence of these substances on human cardiovascular parameters. Thus, this review aims to summarize the most recent clinical data on the intake of these substances and their effects on the cardiovascular system. The present study will help clinicians and other healthcare workers understand the value of flavonol supplementation in both subjects at risk for cardiovascular disease and patients with cardiovascular diseases. View Full-Text
Keywords: flavonols; quercetin; cardiovascular diseases; inflammation flavonols; quercetin; cardiovascular diseases; inflammation
Show Figures

Figure 1

MDPI and ACS Style

Kozłowska, A.; Szostak-Węgierek, D. Targeting Cardiovascular Diseases by Flavonols: An Update. Nutrients 2022, 14, 1439. https://doi.org/10.3390/nu14071439

AMA Style

Kozłowska A, Szostak-Węgierek D. Targeting Cardiovascular Diseases by Flavonols: An Update. Nutrients. 2022; 14(7):1439. https://doi.org/10.3390/nu14071439

Chicago/Turabian Style

Kozłowska, Aleksandra, and Dorota Szostak-Węgierek. 2022. "Targeting Cardiovascular Diseases by Flavonols: An Update" Nutrients 14, no. 7: 1439. https://doi.org/10.3390/nu14071439

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop