Isocaloric Diets with Different Protein-Carbohydrate Ratios: The Effect on Sleep, Melatonin Secretion and Subsequent Nutritional Response in Healthy Young Men
, Emmanuelle Rochette 1,4,5, Giovanna Del Sordo 1, Paul Peyrel 2,6,7, Jérôme Salles 8, Eric Doré 2,3, Etienne Merlin 4,5, Stéphane Walrand 8 and Pascale Duché 1,*Round 1
Reviewer 1 Report
The article is well presented, and the topic can be interesting.
The main problem it has is the sample size, this must be added as a limitation. Even add the n in the tables.
The conclusions must be humble, based on the sample size, with suggestions.
Table 2 can be done with the gain of each group, subtracting the posttest from the pretest, and performing a non-parametric ANCOVA, with spss 28, having the pretest as a covariate.
Author Response
Please find the responses in attached file.
Author Response File: 
Author Response.docx
Reviewer 2 Report
The study design and hypothesis are clear. The paper is well written. There are only a few points that should be addressed:
1. Why the authors enrolled young men that usually do not have problems with sleep?
2. Please provide a study that confirms the validity of melatonin assessment in saliva.
3. Please describe in more detail the study limitations.
4. How the number of study subjects was established?
Author Response
Please find the responses in attached file.
Author Response File: Author Response.docx
Round 2
Reviewer 2 Report
The authors improved the manuscript in line with suggestions.
No further comments.
