Next Article in Journal
Influence of a Nutrigenetic Intervention on Self-Efficacy, Emotions, and Rewarding Behaviors in Unhealthy Eating among Mexicans: An Exploratory Pilot Study
Next Article in Special Issue
Ketoanalogue Supplementation in Patients with Non-Dialysis Diabetic Kidney Disease: A Systematic Review and Meta-Analysis
Previous Article in Journal
Higher Iron Intake Is Independently Associated with Obesity in Younger Japanese Type-2 Diabetes Mellitus Patients
Previous Article in Special Issue
Energy Requirement for Elderly CKD Patients
Review

Interactions between Food and Drugs, and Nutritional Status in Renal Patients: A Narrative Review

Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 56, 56126 Pisa, Italy
*
Author to whom correspondence should be addressed.
Academic Editor: Flávio Reis
Nutrients 2022, 14(1), 212; https://doi.org/10.3390/nu14010212
Received: 21 November 2021 / Revised: 14 December 2021 / Accepted: 16 December 2021 / Published: 4 January 2022
(This article belongs to the Special Issue Nutritional Approach for Patients with Advanced CKD)
Drugs and food interact mutually: drugs may affect the nutritional status of the body, acting on senses, appetite, resting energy expenditure, and food intake; conversely, food or one of its components may affect bioavailability and half-life, circulating plasma concentrations of drugs resulting in an increased risk of toxicity and its adverse effects, or therapeutic failure. Therefore, the knowledge of these possible interactions is fundamental for the implementation of a nutritional treatment in the presence of a pharmacological therapy. This is the case of chronic kidney disease (CKD), for which the medication burden could be a problem, and nutritional therapy plays an important role in the patient’s treatment. The aim of this paper was to review the interactions that take place between drugs and foods that can potentially be used in renal patients, and the changes in nutritional status induced by drugs. A proper definition of the amount of food/nutrient intake, an adequate definition of the timing of meal consumption, and a proper adjustment of the drug dosing schedule may avoid these interactions, safeguarding the quality of life of the patients and guaranteeing the effectiveness of drug therapy. Hence, a close collaboration between the nephrologist, the renal dietitian, and the patient is crucial. Dietitians should consider that food may interact with drugs and that drugs may affect nutritional status, in order to provide the patient with proper dietary suggestions, and to allow the maximum effectiveness and safety of drug therapy, while preserving/correcting the nutritional status. View Full-Text
Keywords: diet; food; nutrients; medication; drug interaction; CKD; nutritional status diet; food; nutrients; medication; drug interaction; CKD; nutritional status
Show Figures

Figure 1

MDPI and ACS Style

D’Alessandro, C.; Benedetti, A.; Di Paolo, A.; Giannese, D.; Cupisti, A. Interactions between Food and Drugs, and Nutritional Status in Renal Patients: A Narrative Review. Nutrients 2022, 14, 212. https://doi.org/10.3390/nu14010212

AMA Style

D’Alessandro C, Benedetti A, Di Paolo A, Giannese D, Cupisti A. Interactions between Food and Drugs, and Nutritional Status in Renal Patients: A Narrative Review. Nutrients. 2022; 14(1):212. https://doi.org/10.3390/nu14010212

Chicago/Turabian Style

D’Alessandro, Claudia, Alessia Benedetti, Antonello Di Paolo, Domenico Giannese, and Adamasco Cupisti. 2022. "Interactions between Food and Drugs, and Nutritional Status in Renal Patients: A Narrative Review" Nutrients 14, no. 1: 212. https://doi.org/10.3390/nu14010212

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop