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Open AccessArticle

Use of Remote Monitoring by E-mail for Long-Term Management of the Classic Ketogenic Diet

1
Human Nutrition and Eating Disorder Research Center, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Via Agostino Bassi, 21, 27100 Pavia, Italy
2
Department of Child Neurology and Psychiatry, IRCCS Mondino Foundation, Via Mondino, 2, 27100 Pavia, Italy
3
Unit of Biostatistics and Clinical Epidemiology, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Via Forlanini, 2, 27100 Pavia, Italy
*
Author to whom correspondence should be addressed.
Member of ERN-EpiCARE.
Nutrients 2020, 12(6), 1833; https://doi.org/10.3390/nu12061833
Received: 24 April 2020 / Revised: 5 June 2020 / Accepted: 17 June 2020 / Published: 19 June 2020
(This article belongs to the Section Clinical Nutrition)
The classic ketogenic diet (cKD) requires constant nutritional monitoring over time both to ensure its effectiveness and to reduce the likelihood of short- and long-term adverse effects. We retrospectively described the use of remote monitoring by e-mail during the first year of follow-up on cKD in 34 children (47% males; age range: 2−17 years) diagnosed with drug-resistant epilepsy (DRE; n = 14) or glucose transporter type 1 deficiency syndrome (GLUT1-DS; n = 20). All the e-mails were evaluated analyzing their frequency and content at 3, 6 and 12 months. Three families never sent e-mails. A median of 36.0 (IQR 23.0–64.0) e-mails per family were sent during the 12 follow-up months by the 31 patients. GLUT1-DS patients sent a greater number of e-mails than the DRE group (median 39.0 (IQR 25.5–56.5) vs. median 26.0 (IQR 19.0–65.0)). At the end of the follow-up period, a greater number of e-mails had been exchanged between the nutritional team and the families belonging to the group that increased its linear growth (median 83.5; IQR 48.0–102.0), compared to the other ones. Constant remote monitoring by e-mail could be a feasible and effective way for a better cKD management. View Full-Text
Keywords: ketogenic diet; drug-resistant epilepsy; glucose transporter type 1 deficiency syndrome; children; monitoring; home management; e-mail ketogenic diet; drug-resistant epilepsy; glucose transporter type 1 deficiency syndrome; children; monitoring; home management; e-mail
MDPI and ACS Style

Ferraris, C.; Guglielmetti, M.; Tamagni, E.; Trentani, C.; De Giorgis, V.; Pasca, L.; Varesio, C.; Ferraro, O.E.; Tagliabue, A. Use of Remote Monitoring by E-mail for Long-Term Management of the Classic Ketogenic Diet. Nutrients 2020, 12, 1833.

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